Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RNF6
  • Mouse genes Rnf6
  • Rat genes Rnf6
  • Zfish genes rnf6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rnf6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Rnf6	IDA		Mouse	PMID:11971979
Molecular Function	GO:0050681	nuclear androgen receptor binding	RNF6	IPI	UniProtKB:P10275	Human	PMID:19345326
Molecular Function	GO:0005515	protein binding	RNF6	IPI	UniProtKB:P10275	Human	PMID:19345326
Molecular Function	GO:0005515	protein binding	Rnf6	IPI	PR:P53668	Mouse	PMID:16204183
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Rnf6	IDA		Mouse	PMID:16204183
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	RNF6	IMP		Human	PMID:19345326
Cellular Component	GO:0030424	axon	Rnf6	IDA		Mouse	PMID:16204183
Cellular Component	GO:0005737	cytoplasm	RNF6	IDA		Human	PMID:19345326
Cellular Component	GO:0005737	cytoplasm	Rnf6	IDA		Mouse	PMID:16204183
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	RNF6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0031965	nuclear membrane	RNF6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	RNF6	IDA		Human	PMID:19345326
Cellular Component	GO:0016605	PML body	Rnf6	IDA		Mouse	PMID:11971979
Biological Process	GO:0048675	axon extension	Rnf6	IMP		Mouse	PMID:16204183
Biological Process	GO:0048675	axon extension	Rnf6	IGI	MGI:MGI:104572	Mouse	PMID:16204183
Biological Process	GO:0030517	negative regulation of axon extension	Rnf6	IMP		Mouse	PMID:16204183
Biological Process	GO:0030517	negative regulation of axon extension	Rnf6	IGI	MGI:MGI:104572	Mouse	PMID:16204183
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	RNF6	IMP		Human	PMID:19345326
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Rnf6	IDA		Mouse	PMID:11971979
Biological Process	GO:0044314	protein K27-linked ubiquitination	RNF6	IDA		Human	PMID:19345326
Biological Process	GO:0070936	protein K48-linked ubiquitination	Rnf6	IMP		Mouse	MGI:MGI:3603857|PMID:16204183
Biological Process	GO:0085020	protein K6-linked ubiquitination	RNF6	IDA		Human	PMID:19345326
Biological Process	GO:0060765	regulation of androgen receptor signaling pathway	RNF6	IMP		Human	PMID:19345326
Biological Process	GO:0006355	regulation of DNA-templated transcription	RNF6	IMP		Human	PMID:19345326
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	Rnf6	IDA		Mouse	PMID:16204183

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern