Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RNF213
  • Mouse genes Rnf213
  • Rat genes Rnf213
  • Zfish genes rnf213a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rnf213

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016887	ATP hydrolysis activity	RNF213	IDA		Human	PMID:21799892
Molecular Function	GO:0016887	ATP hydrolysis activity	RNF213	IDA		Human	PMID:24658080
Molecular Function	GO:0016887	ATP hydrolysis activity	RNF213	IDA		Human	PMID:26126547
Molecular Function	GO:0061630	ubiquitin protein ligase activity	RNF213	IDA		Human	PMID:32139119
Molecular Function	GO:0061630	ubiquitin protein ligase activity	RNF213	IDA		Human	PMID:33842849
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	RNF213	IDA		Human	PMID:21799892
Cellular Component	GO:0005737	cytoplasm	RNF213	IDA		Human	PMID:21799892
Cellular Component	GO:0005829	cytosol	RNF213	IDA		Human	PMID:34012115
Cellular Component	GO:0005829	cytosol	RNF213	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	RNF213	IDA		Human	PMID:30705059
Cellular Component	GO:0005811	lipid droplet	RNF213	IDA		Human	PMID:30705059
Cellular Component	GO:0016020	membrane	RNF213	HDA		Human	PMID:19946888
Cellular Component	GO:0005730	nucleolus	RNF213	IDA		Human	GO_REF:0000052
Biological Process	GO:0001525	angiogenesis	RNF213	IMP		Human	PMID:26126547
Biological Process	GO:0001525	angiogenesis	RNF213	IMP		Human	PMID:26278786
Biological Process	GO:0001525	angiogenesis	Rnf213	IMP		Mouse	MGI:MGI:5751632|PMID:26126547
Biological Process	GO:0008015	blood circulation	rnf213a	IMP	ZFIN:ZDB-GENO-180614-7	Zfish	PMID:27125596
Biological Process	GO:0008015	blood circulation	rnf213a	IMP	ZFIN:ZDB-GENO-180614-4	Zfish	PMID:27125596
Biological Process	GO:0042742	defense response to bacterium	RNF213	IDA		Human	PMID:34012115
Biological Process	GO:0042742	defense response to bacterium	Rnf213	IMP		Mouse	MGI:MGI:6729754|PMID:34012115
Biological Process	GO:0140042	lipid droplet formation	RNF213	IDA		Human	PMID:30705059
Biological Process	GO:0140042	lipid droplet formation	rnf213a	IMP		Zfish	PMID:30705059|ZFIN:ZDB-PUB-200211-10
Biological Process	GO:0120323	lipid ubiquitination	RNF213	IDA		Human	PMID:34012115
Biological Process	GO:0120323	lipid ubiquitination	Rnf213	IMP		Mouse	MGI:MGI:6729754|PMID:34012115
Biological Process	GO:2000051	negative regulation of non-canonical Wnt signaling pathway	RNF213	IMP		Human	PMID:26766444
Biological Process	GO:0051865	protein autoubiquitination	RNF213	IDA		Human	PMID:21799892
Biological Process	GO:0070534	protein K63-linked ubiquitination	RNF213	IDA		Human	PMID:32139119
Biological Process	GO:0070534	protein K63-linked ubiquitination	RNF213	IDA		Human	PMID:33842849
Biological Process	GO:0016567	protein ubiquitination	RNF213	IDA		Human	PMID:21799892
Biological Process	GO:0045765	regulation of angiogenesis	rnf213a	IMP	ZFIN:ZDB-GENO-180614-6	Zfish	PMID:32248732
Biological Process	GO:0045765	regulation of angiogenesis	rnf213a	IMP	ZFIN:ZDB-GENO-221128-4	Zfish	PMID:32248732
Biological Process	GO:0019216	regulation of lipid metabolic process	RNF213	IDA		Human	PMID:30705059
Biological Process	GO:0002040	sprouting angiogenesis	RNF213	IMP		Human	PMID:26766444
Biological Process	GO:0002040	sprouting angiogenesis	rnf213a	IMP	ZFIN:ZDB-GENO-180614-7	Zfish	PMID:27125596
Biological Process	GO:0002040	sprouting angiogenesis	rnf213a	IMP	ZFIN:ZDB-GENO-180614-4	Zfish	PMID:27125596
Biological Process	GO:0002040	sprouting angiogenesis	rnf213a	IMP	ZFIN:ZDB-MRPHLNO-110822-11,ZFIN:ZDB-MRPHLNO-110822-12	Zfish	PMID:21799892
Biological Process	GO:0002040	sprouting angiogenesis	rnf213a	IMP	ZFIN:ZDB-MRPHLNO-110822-13,ZFIN:ZDB-MRPHLNO-110822-14	Zfish	PMID:21799892
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	RNF213	IMP		Human	PMID:26766444
Biological Process	GO:0098792	xenophagy	RNF213	IDA		Human	PMID:34012115

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern