Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RNF139
  • Mouse genes Rnf139
  • Rat genes Rnf139
  • Zfish genes rnf139
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rnf139

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0002020	protease binding	RNF139	IPI	UniProtKB:Q8TCT9	Human	PMID:25239945
Molecular Function	GO:0005515	protein binding	RNF139	IPI	UniProtKB:P40337	Human	PMID:12032852
Molecular Function	GO:0005515	protein binding	RNF139	IPI	UniProtKB:O95487	Human	PMID:19706601
Molecular Function	GO:0005515	protein binding	RNF139	IPI	UniProtKB:Q12770	Human	PMID:19706601
Molecular Function	GO:0005515	protein binding	RNF139	IPI	UniProtKB:Q12772	Human	PMID:19706601
Molecular Function	GO:0005515	protein binding	RNF139	IPI	UniProtKB:Q8TCT9	Human	PMID:19720873
Molecular Function	GO:0005515	protein binding	RNF139	IPI	UniProtKB:Q9Y679	Human	PMID:23223569
Molecular Function	GO:0005515	protein binding	RNF139	IPI	UniProtKB:P17861-1	Human	PMID:25239945
Molecular Function	GO:0005515	protein binding	RNF139	IPI	UniProtKB:Q8TCT9	Human	PMID:25239945
Molecular Function	GO:0005515	protein binding	RNF139	IPI	UniProtKB:P54253	Human	PMID:32814053
Molecular Function	GO:0019787	ubiquitin-like protein transferase activity	RNF139	IDA		Human	PMID:17016439
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	RNF139	IDA		Human	PMID:17016439
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	RNF139	IMP		Human	PMID:19720873
Cellular Component	GO:0036513	Derlin-1 retrotranslocation complex	RNF139	IDA		Human	PMID:25239945
Cellular Component	GO:0005783	endoplasmic reticulum	RNF139	IDA		Human	PMID:12032852
Biological Process	GO:0036503	ERAD pathway	RNF139	IMP		Human	PMID:25239945
Biological Process	GO:0008285	negative regulation of cell population proliferation	RNF139	IDA		Human	PMID:17016439
Biological Process	GO:0017148	negative regulation of translation	RNF139	IDA		Human	PMID:20068067
Biological Process	GO:2000060	positive regulation of ubiquitin-dependent protein catabolic process	RNF139	IMP		Human	PMID:25239945
Biological Process	GO:0031648	protein destabilization	RNF139	IMP		Human	PMID:25239945
Biological Process	GO:0016567	protein ubiquitination	RNF139	IDA		Human	PMID:10500182
Biological Process	GO:0016567	protein ubiquitination	RNF139	IDA		Human	PMID:17016439
Biological Process	GO:0016567	protein ubiquitination	RNF139	IMP		Human	PMID:19720873
Biological Process	GO:0060628	regulation of ER to Golgi vesicle-mediated transport	RNF139	IDA		Human	PMID:19706601
Biological Process	GO:0070613	regulation of protein processing	RNF139	IDA		Human	PMID:19706601

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern