Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RGS3
  • Mouse genes Rgs3
  • Rat genes Rgs3
  • Zfish genes rgs3a,rgs3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rgs3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	RGS3	IPI	UniProtKB:Q96AP0	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	RGS3	IPI	UniProtKB:O15162	Human	PMID:25416956
Cellular Component	GO:0005634	nucleus	Rgs3	IDA		Mouse	PMID:11034339
Cellular Component	GO:0005886	plasma membrane	RGS3	IDA		Human	GO_REF:0000052
Biological Process	GO:0045812	negative regulation of Wnt signaling pathway, calcium modulating pathway	rgs3a	IMP	ZFIN:ZDB-MRPHLNO-110523-7	Zfish	PMID:20628572
Biological Process	GO:0008591	regulation of Wnt signaling pathway, calcium modulating pathway	rgs3a	IGI	ZFIN:ZDB-MRPHLNO-090915-1	Zfish	PMID:20628572
Biological Process	GO:0007165	signal transduction	Rgs3	IDA		Rat	PMID:12006602|RGD:625585
Biological Process	GO:0061053	somite development	rgs3a	IMP	ZFIN:ZDB-MRPHLNO-100726-6	Zfish	PMID:20628572
Biological Process	GO:0061053	somite development	rgs3a	IGI	ZFIN:ZDB-MRPHLNO-090915-1	Zfish	PMID:20628572

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern