Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RFXANK
  • Mouse genes Rfxank
  • Rat genes Rfxank
  • Zfish genes rfxank
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rfxank

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	RFXANK	IDA		Human	PMID:9806546
Molecular Function	GO:0042826	histone deacetylase binding	Rfxank	IDA		Mouse	PMID:16236793
Molecular Function	GO:0005515	protein binding	RFXANK	IPI	UniProtKB:O00287	Human	PMID:10938133
Molecular Function	GO:0005515	protein binding	RFXANK	IPI	UniProtKB:P48382	Human	PMID:10938133
Molecular Function	GO:0005515	protein binding	RFXANK	IPI	UniProtKB:P48382	Human	PMID:20211142
Molecular Function	GO:0005515	protein binding	RFXANK	IPI	UniProtKB:O00287	Human	PMID:25752541
Molecular Function	GO:0005515	protein binding	RFXANK	IPI	UniProtKB:P48382	Human	PMID:25752541
Molecular Function	GO:0005515	protein binding	RFXANK	IPI	UniProtKB:Q2KHR2	Human	PMID:25752541
Molecular Function	GO:0005515	protein binding	RFXANK	IPI	UniProtKB:Q2KHR2	Human	PMID:31864703
Molecular Function	GO:0005515	protein binding	Rfxank	IPI	UniProtKB:Q9UQL6	Mouse	PMID:16236793
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	RFXANK	IDA		Human	PMID:9806546
Cellular Component	GO:0005737	cytoplasm	Rfxank	IDA		Mouse	PMID:10329666
Cellular Component	GO:0005829	cytosol	RFXANK	IDA		Human	GO_REF:0000052
Cellular Component	GO:0045171	intercellular bridge	RFXANK	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	RFXANK	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	RFXANK	IDA		Human	PMID:10938133
Cellular Component	GO:0005634	nucleus	Rfxank	IGI	UniProtKB:Q9UQL6	Mouse	PMID:16236793
Cellular Component	GO:0005634	nucleus	Rfxank	IDA		Mouse	PMID:10329666
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	RFXANK	IPI		Human	PMID:10938133
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	RFXANK	IPI	UniProtKB:O00287|UniProtKB:P48382	Human	PMID:9806546
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	RFXANK	IDA		Human	PMID:10938133
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	RFXANK	IDA		Human	PMID:9806546
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Rfxank	IDA		Mouse	PMID:16236793
Biological Process	GO:0007265	Ras protein signal transduction	Rfxank	IPI	PR:Q99N57	Mouse	PMID:10329666

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern