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Rfxank
Gene Detail
Symbol

Name
ID
Rfxank
regulatory factor X-associated ankyrin-containing protein
MGI:1333865
Synonyms
Tvl1
Feature Type
protein coding gene
Genetic Map
Chromosome 8
34.15 cM, cytoband C1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr8:70130812-70139197 bp, - strand
From Ensembl annotation of GRCm38

  8386 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2760  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: RFXANK
Protein SuperFamily: DNA-binding protein RFXANK
Gene Tree: Rfxank

Human
homologs
RFXANK, regulatory factor X-associated ankyrin-containing protein
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 8625
neXtProt AC: NX_O14593

Human Synonyms: ANKRA1, BLS, F14150_1, RFX-B

Human Chr (Location): 19p12; chr19:19192199-19201869 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human RFXANK

Mutations,
alleles, and
phenotypes
All mutations/alleles(16) : Gene trapped(13) Targeted(3)
Interactions
Rfxank interacts with 241 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (3 records)
Data Summary: Results (160)    Tissues (137)    Images (15)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 160
cDNA source data(16)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: GEISHA RFXANK ; Xenbase rfxank    NEW 
Molecular
reagents
All nucleic(18) cDNA(18)
Microarray probesets(6)
Other database
links
Ensembl Gene Model ENSMUSG00000036120 (Evidence)
Entrez Gene 19727 (Evidence)
NIA Mouse Gene Index U029908
Consensus CDS Project CCDS22360.1
International Mouse Phenotyping Consortium Status Rfxank
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000036120 Ensembl Gene Model | MGI Sequence Detail 8386 C57BL/6J ±  kb
transcript ENSMUST00000075724 Ensembl | MGI Sequence Detail 3676 Not Applicable 
polypeptide ENSMUSP00000075140 Ensembl | MGI Sequence Detail 269 Not Applicable 

For the selected sequences
All sequences(28) RefSeq(4) UniProt(4)
Polymorphisms
SNPs within 2kb(118 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR002110 Ankyrin repeat
InterPro IPR020683 Ankyrin repeat-containing domain
InterPro IPR017362 DNA-binding, RFXANK
Protein Ontology PR:000013930 DNA-binding protein RFXANK
References
(Earliest) J:50539 Masternak K, et al., A gene encoding a novel RFX-associated transactivator is mutated in the majority of MHC class II deficiency patients. Nat Genet. 1998 Nov;20(3):273-7
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(34)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory