Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RDH12
  • Mouse genes Rdh12
  • Rat genes Rdh12
  • Zfish genes rdh12,si:dkey-73n8.3,si:dkey-94e7.2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rdh12

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004745	NAD-retinol dehydrogenase activity	RDH12	IDA		Human	PMID:12226107
Molecular Function	GO:0004745	NAD-retinol dehydrogenase activity	Rdh12	IDA		Mouse	MGI:MGI:5442470|PMID:22621924
Molecular Function	GO:0052650	NADP-retinol dehydrogenase activity	RDH12	IDA		Human	PMID:12226107
Molecular Function	GO:0005515	protein binding	RDH12	IPI	UniProtKB:P0CG48	Human	PMID:20006610
Molecular Function	GO:0005515	protein binding	RDH12	IPI	UniProtKB:Q93062	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RDH12	IPI	UniProtKB:Q93062-3	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	RDH12	IPI	UniProtKB:Q6IQ23-2	Human	PMID:32296183
Cellular Component	GO:0001917	photoreceptor inner segment	Rdh12	IDA		Mouse	MGI:MGI:6271140|PMID:12226107
Biological Process	GO:0110095	cellular detoxification of aldehyde	RDH12	IDA		Human	PMID:19686838
Biological Process	GO:0110095	cellular detoxification of aldehyde	Rdh12	IDA		Mouse	MGI:MGI:5442470|PMID:22621924
Biological Process	GO:0042572	retinol metabolic process	RDH12	IDA		Human	PMID:12226107
Biological Process	GO:0042572	retinol metabolic process	Rdh12	IDA		Mouse	MGI:MGI:5442470|PMID:22621924
Biological Process	GO:0007601	visual perception	RDH12	IMP		Human	PMID:12226107
Biological Process	GO:0007601	visual perception	Rdh12	IMP		Mouse	MGI:MGI:3696600|PMID:17032653

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern