Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RAB8B
  • Mouse genes Rab8b
  • Rat genes Rab8b
  • Zfish genes rab8b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rab8b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019003	GDP binding	RAB8B	IDA		Human	PMID:20937701
Molecular Function	GO:0005515	protein binding	RAB8B	IPI	UniProtKB:Q96CV9	Human	PMID:17646400
Molecular Function	GO:0005515	protein binding	Rab8b	IPI	UniProtKB:Q3TN34	Mouse	MGI:MGI:5508599|PMID:18094055
Molecular Function	GO:0005515	protein binding	Rab8b	IPI	UniProtKB:Q9ESF1	Mouse	MGI:MGI:3692845|PMID:17055430
Molecular Function	GO:0005515	protein binding	Rab8b	IPI	UniProtKB:P31000	Rat	PMID:12639940|RGD:8554779
Molecular Function	GO:0005515	protein binding	Rab8b	IPI	UniProtKB:Q9R0T4	Rat	PMID:12639940|RGD:8554779
Molecular Function	GO:0005515	protein binding	Rab8b	IPI	RGD:620646	Rat	PMID:18772196|RGD:9491383
Molecular Function	GO:0005102	signaling receptor binding	RAB8B	IPI	UniProtKB:P50542	Human	PMID:18346465
Molecular Function	GO:0005102	signaling receptor binding	RAB8B	IPI	UniProtKB:Q8IYB4	Human	PMID:18346465
Molecular Function	GO:0030911	TPR domain binding	Rab8b	IPI	RGD:708407	Rat	PMID:11278749|RGD:737646
Cellular Component	GO:0051286	cell tip	Rab8b	IDA		Rat	PMID:11278749|RGD:737646
Cellular Component	GO:0031410	cytoplasmic vesicle	Rab8b	IDA		Rat	PMID:8799816|RGD:2306458
Cellular Component	GO:0070062	extracellular exosome	RAB8B	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	RAB8B	HDA		Human	PMID:20458337
Cellular Component	GO:0005739	mitochondrion	Rab8b	HDA		Mouse	PMID:18614015
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Rab8b	IDA		Rat	PMID:11278749|RGD:737646
Cellular Component	GO:0005778	peroxisomal membrane	RAB8B	IDA		Human	PMID:18346465
Cellular Component	GO:0045335	phagocytic vesicle	RAB8B	IDA		Human	PMID:21255211
Cellular Component	GO:0005886	plasma membrane	Rab8b	IDA		Rat	PMID:8799816|RGD:2306458
Cellular Component	GO:0098793	presynapse	Rab8b	EXP		Rat	PMID:20926670|RGD:13432355
Cellular Component	GO:0098793	presynapse	Rab8b	IDA		Rat	PMID:20926670|RGD:13432355
Cellular Component	GO:0098793	presynapse	Rab8b	IMP		Rat	PMID:20926670|RGD:13432355
Biological Process	GO:0019882	antigen processing and presentation	RAB8B	IMP		Human	PMID:19717423
Biological Process	GO:0150115	cell-substrate junction organization	Rab8b	IDA		Rat	PMID:12639940|RGD:8554779
Biological Process	GO:0031346	positive regulation of cell projection organization	Rab8b	IDA		Rat	PMID:11278749|RGD:737646
Biological Process	GO:0051461	positive regulation of corticotropin secretion	Rab8b	IDA		Rat	PMID:11278749|RGD:737646
Biological Process	GO:0045046	protein import into peroxisome membrane	RAB8B	IDA		Human	PMID:18346465
Biological Process	GO:0060828	regulation of canonical Wnt signaling pathway	rab8b	IMP	ZFIN:ZDB-MRPHLNO-140124-3	Zfish	PMID:24035388

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern