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Rab8b Gene Detail
Summary
  • Symbol
    Rab8b
  • Name
    RAB8B, member RAS oncogene family
  • Synonyms
    D330025I23Rik, Rab8b
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442982
    NCBI Gene: 235442
  • Gene Overview
    MyGene.info: RAB8B
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:66843664-66919687 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 36.17 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    337 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442982
protein coding gene Chr9:66843664-66919705 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034982
protein coding gene Chr9:66723308-66798802 (-)
A/J MGP_AJ_G0034962
protein coding gene Chr9:64407871-64486146 (-)
AKR/J MGP_AKRJ_G0034892
protein coding gene Chr9:65944055-66021783 (-)
BALB/cJ MGP_BALBcJ_G0034955
protein coding gene Chr9:64140647-64217837 (-)
C3H/HeJ MGP_C3HHeJ_G0034664
protein coding gene Chr9:66477983-66558008 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035474
protein coding gene Chr9:68542257-68622086 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032385
protein coding gene Chr9:64041179-64116494 (-)
CAST/EiJ MGP_CASTEiJ_G0033986
protein coding gene Chr9:66705871-66787735 (-)
CBA/J MGP_CBAJ_G0034636
protein coding gene Chr9:70887783-70972380 (-)
DBA/2J MGP_DBA2J_G0034795
protein coding gene Chr9:64179387-64254450 (-)
FVB/NJ MGP_FVBNJ_G0034737
protein coding gene Chr9:63520733-63598176 (-)
LP/J MGP_LPJ_G0034877
protein coding gene Chr9:66993826-67074538 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034779
protein coding gene Chr9:72116309-72198964 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035496
protein coding gene Chr9:66058559-66141336 (-)
PWK/PhJ MGP_PWKPhJ_G0033690
protein coding gene Chr9:64406887-64483485 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033523
protein coding gene Chr9:66372879-66450127 (-)
WSB/EiJ MGP_WSBEiJ_G0034098
protein coding gene Chr9:65958338-66035575 (-)



Homology
more
  • Human Ortholog
    RAB8B, RAB8B, member RAS oncogene family
  • Vertebrate Orthologs
    10
  • Human Ortholog
    RAB8B, RAB8B, member RAS oncogene family
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 51762
    neXtProt AC: NX_Q92930
    UniProt: Q92930

  • Chr Location
    15q22.2; chr15:63189529-63267776 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotypes from multigenic genotypes
    7 phenotype references
Mice homozygous for a knock-out allele exhibit no overt abnormalities and normal survival.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000036943 Ensembl Gene Model | MGI Sequence Detail 76024 C57BL/6J ±  kb
transcript ENSMUST00000041139 Ensembl | MGI Sequence Detail 4733 Not Applicable  
polypeptide ENSMUSP00000041857 Ensembl | MGI Sequence Detail 207 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 88
    cDNA 88

    Microarray probesets 3
References
more
  • Summaries
    All 35
    Developmental Gene Expression 1
    Gene Ontology 9
    Phenotypes 7
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:260459 Azizoglu DB, et al., Afadin and RhoA control pancreatic endocrine mass via lumen morphogenesis. Genes Dev. 2017 Dec 1;31(23-24):2376-2390

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory