Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RAB27B
  • Mouse genes Rab27b
  • Rat genes Rab27b
  • Zfish genes rab27b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rab27b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019003	GDP binding	RAB27B	IDA		Human	PMID:20937701
Molecular Function	GO:0005525	GTP binding	RAB27B	IDA		Human	PMID:9066979
Molecular Function	GO:0005525	GTP binding	Rab27b	IDA		Mouse	MGI:MGI:4412434|PMID:18940604
Molecular Function	GO:0003924	GTPase activity	Rab27b	IDA		Mouse	MGI:MGI:4412434|PMID:18940604
Molecular Function	GO:0031489	myosin V binding	RAB27B	IPI	UniProtKB:Q9Y4I1	Human	PMID:15357836
Molecular Function	GO:0005515	protein binding	RAB27B	IPI	UniProtKB:Q9BV36	Human	PMID:15357836
Molecular Function	GO:0005515	protein binding	RAB27B	IPI	UniProtKB:Q03135	Human	PMID:19706440
Molecular Function	GO:0005515	protein binding	RAB27B	IPI	UniProtKB:P49366	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RAB27B	IPI	UniProtKB:Q8TDW5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RAB27B	IPI	UniProtKB:Q8TDW5	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	RAB27B	IPI	UniProtKB:Q8TCE6	Human	PMID:30771381
Molecular Function	GO:0005515	protein binding	RAB27B	IPI	UniProtKB:Q8TDW5	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	RAB27B	IPI	UniProtKB:P49366	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RAB27B	IPI	UniProtKB:Q8NFW9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RAB27B	IPI	UniProtKB:Q8TDW5-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RAB27B	IPI	UniProtKB:Q9BV36	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RAB27B	IPI	UniProtKB:Q9H8Y8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RAB27B	IPI	UniProtKB:Q9UNE2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RAB27B	IPI	UniProtKB:Q9Y2J0-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Rab27b	IPI	UniProtKB:Q99N50	Mouse	MGI:MGI:3693417|PMID:16716193
Molecular Function	GO:0005515	protein binding	Rab27b	IPI	UniProtKB:Q91V27	Mouse	MGI:MGI:4412434|PMID:18940604
Molecular Function	GO:0005515	protein binding	Rab27b	IPI	PR:Q768S4	Mouse	PMID:12578829
Molecular Function	GO:0005515	protein binding	Rab27b	IPI	RGD:620918|RGD:620114	Rat	PMID:15039459|RGD:4892230
Molecular Function	GO:0005515	protein binding	Rab27b	IPI	RGD:620342	Rat	PMID:17067543|RGD:1601610
Molecular Function	GO:0019904	protein domain specific binding	RAB27B	IPI	UniProtKB:Q8NEV8	Human	PMID:16880209
Cellular Component	GO:0016324	apical plasma membrane	Rab27b	IDA		Rat	PMID:17067543|RGD:1601610
Cellular Component	GO:0070062	extracellular exosome	RAB27B	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	RAB27B	HDA		Human	PMID:23533145
Cellular Component	GO:0005794	Golgi apparatus	Rab27b	IDA		Mouse	PMID:14724135
Cellular Component	GO:0005795	Golgi stack	RAB27B	IDA		Human	PMID:19966785
Cellular Component	GO:0005770	late endosome	RAB27B	IDA		Human	PMID:30771381
Cellular Component	GO:0042470	melanosome	RAB27B	IDA		Human	PMID:15357836
Cellular Component	GO:0032585	multivesicular body membrane	RAB27B	IDA		Human	PMID:19966785
Cellular Component	GO:0030667	secretory granule membrane	Rab27b	IDA		Rat	PMID:17067543|RGD:1601610
Cellular Component	GO:0030672	synaptic vesicle membrane	Rab27b	EXP		Rat	PMID:20926670|RGD:13432355
Cellular Component	GO:0030672	synaptic vesicle membrane	Rab27b	IDA		Rat	PMID:20926670|RGD:13432355
Cellular Component	GO:0030140	trans-Golgi network transport vesicle	RAB27B	IDA		Human	PMID:19966785
Cellular Component	GO:0042589	zymogen granule membrane	Rab27b	IDA		Rat	PMID:15451418|RGD:1303344
Biological Process	GO:0099641	anterograde axonal protein transport	Rab27b	IMP		Rat	PMID:21775604|RGD:13673858
Biological Process	GO:0071985	multivesicular body sorting pathway	RAB27B	IMP		Human	PMID:19966785
Biological Process	GO:0045921	positive regulation of exocytosis	RAB27B	IMP		Human	PMID:19966785
Biological Process	GO:0017157	regulation of exocytosis	Rab27b	IDA		Rat	PMID:15451418|RGD:1303344
Biological Process	GO:0048488	synaptic vesicle endocytosis	Rab27b	IDA		Rat	PMID:20926670|RGD:13432355
Biological Process	GO:0048488	synaptic vesicle endocytosis	Rab27b	IMP		Rat	PMID:20926670|RGD:13432355

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern