Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RAB18
  • Mouse genes Rab18
  • Rat genes Rab18
  • Zfish genes rab18a,rab18b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rab18

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019003	GDP binding	RAB18	IDA		Human	PMID:20937701
Molecular Function	GO:0005515	protein binding	RAB18	IPI	UniProtKB:Q99IB8:PRO_0000045602	Human	PMID:23935497
Molecular Function	GO:0005515	protein binding	RAB18	IPI	UniProtKB:Q15042	Human	PMID:24891604
Molecular Function	GO:0005515	protein binding	RAB18	IPI	UniProtKB:Q9H2M9	Human	PMID:24891604
Molecular Function	GO:0005515	protein binding	RAB18	IPI	UniProtKB:Q86VP1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	RAB18	IPI	UniProtKB:O43264	Human	PMID:30970241
Molecular Function	GO:0005515	protein binding	RAB18	IPI	UniProtKB:Q96G97	Human	PMID:30970241
Molecular Function	GO:0005515	protein binding	RAB18	IPI	UniProtKB:Q9HBF4	Human	PMID:30970241
Molecular Function	GO:0005515	protein binding	RAB18	IPI	UniProtKB:Q9HBF4	Human	PMID:31293035
Molecular Function	GO:0005515	protein binding	RAB18	IPI	UniProtKB:Q13520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	RAB18	IPI	UniProtKB:Q9GZR5	Human	PMID:32296183
Cellular Component	GO:0071782	endoplasmic reticulum tubular network	RAB18	IDA		Human	PMID:24891604
Cellular Component	GO:0005811	lipid droplet	RAB18	IDA		Human	PMID:30970241
Cellular Component	GO:0045202	synapse	Rab18	EXP		Rat	PMID:24876496|RGD:10047219
Cellular Component	GO:0045202	synapse	Rab18	IDA		Rat	PMID:24876496|RGD:10047219
Biological Process	GO:0007420	brain development	rab18b	IMP		Zfish	PMID:21473985|ZFIN:ZDB-PUB-110512-8
Biological Process	GO:0043009	chordate embryonic development	rab18a	IMP	ZFIN:ZDB-MRPHLNO-110516-2	Zfish	PMID:21473985
Biological Process	GO:0043009	chordate embryonic development	rab18a	IMP	ZFIN:ZDB-MRPHLNO-110516-1	Zfish	PMID:21473985
Biological Process	GO:0043009	chordate embryonic development	rab18b	IMP	ZFIN:ZDB-MRPHLNO-110516-4	Zfish	PMID:21473985
Biological Process	GO:0071786	endoplasmic reticulum tubular network organization	RAB18	IMP		Human	PMID:24891604
Biological Process	GO:0001654	eye development	rab18b	IMP		Zfish	PMID:21473985|ZFIN:ZDB-PUB-110512-8
Biological Process	GO:0001654	eye development	rab18a	IMP	ZFIN:ZDB-MRPHLNO-110516-2	Zfish	PMID:21473985
Biological Process	GO:0001654	eye development	rab18a	IMP	ZFIN:ZDB-MRPHLNO-110516-1	Zfish	PMID:21473985
Biological Process	GO:0001654	eye development	rab18b	IMP	ZFIN:ZDB-MRPHLNO-110516-4	Zfish	PMID:21473985
Biological Process	GO:0051170	import into nucleus	Rab18	IMP		Mouse	MGI:MGI:5810251|PMID:26021350
Biological Process	GO:0034389	lipid droplet organization	RAB18	IMP		Human	PMID:24239381

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern