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Rab18
Gene Detail
 Symbol
Name
ID
Rab18
RAB18, member RAS oncogene family
MGI:102790
Feature Type protein coding gene
Genetic Map
Chromosome 18
4.53 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr18:6765205-6790231 bp, + strand
From NCBI annotation of GRCm38

  25027 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:40765  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: Ras-related protein Rab
Gene Tree: Rab18

Human
homologs
Human Homolog RAB18, RAB18, member RAS oncogene family
NCBI Gene ID 22931
neXtProt AC  NX_Q9NP72
Human Synonyms  RAB18LI1, WARBM3
Human Chr (Location)  10p12.1; chr10:27504174-27542237 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human RAB18
Mutations,
alleles, and
phenotypes
All mutations/alleles(25) : Gene trapped(24) Targeted(1)
Interactions
Rab18 interacts with 273 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process lipid particle organization, multicellular organismal development, ...
Component extracellular vesicular exosome, intracellular, ...
Function GDP binding, GTP binding, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (56)    Tissues (42)    Images (13)
Theiler Stages: 15, 17, 19, 22, 23, 24, 28
Assay TypeResults
RNA in situ 56
cDNA source data(191)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(191) cDNA(191)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000073639 (Evidence)
Entrez Gene19330 (Evidence)
UniGene132802
DFCITC1573570, TC1611585
DoTSDT.101283792, DT.110784408, DT.534966
NIA Mouse Gene IndexU018378
Consensus CDS ProjectCCDS29044.1
International Mouse Knockout Project StatusRab18
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 19330 NCBI Gene Model | MGI Sequence Detail 25027 C57BL/6J ±  kb
transcript NM_001278447 RefSeq | MGI Sequence Detail 3688 C57BL/6 
polypeptide P35293 UniProt | EBI | MGI Sequence Detail 206 Not Applicable 

For the selected sequences
All sequences(46) RefSeq(4) UniProt(3)
Polymorphisms RFLP(1) : SNPs within 2kb(78 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR025662 Sigma-54 interaction domain, ATP-binding site 1
InterPro IPR001806 Small GTPase superfamily
InterPro IPR003579 Small GTPase superfamily, Rab type
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000013589 ras-related protein Rab-18
Graphical View of Protein Domain Structure
References (Earliest) J:24144 Chavrier P, et al., The complexity of the Rab and Rho GTP-binding protein subfamilies revealed by a PCR cloning approach. Gene. 1992 Mar 15;112(2):261-4
(Latest) J:206668 Liegel RP, et al., Loss-of-function mutations in TBC1D20 cause cataracts and male infertility in blind sterile mice and Warburg micro syndrome in humans. Am J Hum Genet. 2013 Dec 5;93(6):1001-14
All references(44)
Other
accession IDs
MGD-MRK-19698, MGI:2147186

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory