Rab18
Gene Detail

Symbol Name ID

Rab18 RAB18, member RAS oncogene family MGI:102790

Feature Type

protein coding gene

Genetic Map

Chromosome 18

4.53 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr18:6765205-6790231 bp, + strand From NCBI annotation of GRCm38   25027 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:40765  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: Ras-related protein Rab
Gene Tree: Rab18

Human homologs

Human Homolog		RAB18, RAB18, member RAS oncogene family
NCBI Gene ID		22931
neXtProt AC		NX_Q9NP72
Human Synonyms		RAB18LI1, WARBM3
Human Chr (Location)		10p12.1; chr10:27793103-27831166 (+)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human RAB18

Alleles and phenotypes

All alleles(25) : Targeted(1) Gene trapped(24)

Gene Ontology (GO) classifications

All GO classifications: (12 annotations)

Process	multicellular organismal development, protein transport, ...
Component	intracellular, membrane, ...
Function	GDP binding, GTP binding, ...

External Resources: FuncBase

Expression

Literature Summary: (4 records)
Data Summary: Results (56)    Tissues (42)    Images (13)
Theiler Stages: 15, 17, 19, 22, 23, 24, 28

Assay Type	Results
RNA in situ	56

cDNA source data(22)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(22) cDNA(22)
Microarray probesets(4)

Other database links

Ensembl Gene Model	ENSMUSG00000073639 (Evidence)
Entrez Gene	19330 (Evidence)
DFCI	TC1573570, TC1611585
DoTS	DT.101283792, DT.534966
NIA Mouse Gene Index	U018378
Consensus CDS Project	CCDS29044.1
International Mouse Knockout Project Status	Rab18

Sequences

Length	Strain/Species
genomic	19330	NCBI Gene Model | MGI Sequence Detail	25027	C57BL/6J
transcript	NM_181070	RefSeq | MGI Sequence Detail	2257	C57BL/6
polypeptide	P35293	UniProt | EBI | MGI Sequence Detail	206	Not Applicable

All sequences(39) RefSeq(2) UniProt(3)

Polymorphisms

RFLP(1) : SNPs(54 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR025662	Sigma-54 interaction domain, ATP-binding site 1
InterPro	IPR001806	Small GTPase superfamily
InterPro	IPR003579	Small GTPase superfamily, Rab type
InterPro	IPR005225	Small GTP-binding protein domain
Protein Ontology	PR:000013589	ras-related protein Rab-18

Graphical View of Protein Domain Structure

References

(Earliest) J:24144 Chavrier P, et al., The complexity of the Rab and Rho GTP-binding protein subfamilies revealed by a PCR cloning approach. Gene. 1992 Mar 15;112(2):261-4
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(42)

Other accession IDs

MGD-MRK-19698, MGI:2147186