About   Help   FAQ
Rab18
Gene Detail
Symbol

Name
ID
Rab18
RAB18, member RAS oncogene family
MGI:102790
Feature Type
protein coding gene
Genetic Map
Chromosome 18
4.53 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr18:6765205-6790231 bp, + strand
From Ensembl annotation of GRCm38

  25027 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:40765  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: Ras-related protein Rab
Gene Tree: Rab18

Human
homologs
Human Homolog RAB18, RAB18, member RAS oncogene family
NCBI Gene ID 22931
neXtProt AC  NX_Q9NP72
Human Synonyms  RAB18LI1, WARBM3
Human Chr (Location)  10p12.1; chr10:27504174-27542237 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human RAB18
Mutations,
alleles, and
phenotypes
All mutations/alleles(25) : Gene trapped(24) Targeted(1)
Interactions
Rab18 interacts with 273 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (4 records)
Data Summary: Results (56)    Tissues (42)    Images (13)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 56
cDNA source data(191)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(191) cDNA(191)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000073639 (Evidence)
Entrez Gene19330 (Evidence)
UniGene132802
DFCITC1611585, TC1573570
DoTSDT.110784408, DT.101283792, DT.534966
NIA Mouse Gene IndexU018378
Consensus CDS ProjectCCDS29044.1
International Mouse Knockout Project StatusRab18
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000073639 Ensembl Gene Model | MGI Sequence Detail 25027 C57BL/6J ±  kb
transcript ENSMUST00000097680 Ensembl | MGI Sequence Detail 2257 Not Applicable 
polypeptide ENSMUSP00000095285 Ensembl | MGI Sequence Detail 206 Not Applicable 

For the selected sequences
All sequences(48) RefSeq(4) UniProt(5)
Polymorphisms
RFLP(1) : SNPs within 2kb(78 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR025662 Sigma-54 interaction domain, ATP-binding site 1
InterPro IPR001806 Small GTPase superfamily
InterPro IPR003579 Small GTPase superfamily, Rab type
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000013589 ras-related protein Rab-18
References
(Earliest) J:24144 Chavrier P, et al., The complexity of the Rab and Rho GTP-binding protein subfamilies revealed by a PCR cloning approach. Gene. 1992 Mar 15;112(2):261-4
(Latest) J:211808 Carpanini SM, et al., A novel mouse model of Warburg Micro syndrome reveals roles for RAB18 in eye development and organisation of the neuronal cytoskeleton. Dis Model Mech. 2014 Jun;7(6):711-22
All references(46)
Other
accession IDs
MGD-MRK-19698, MGI:2147186

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/09/2014
MGI 5.20
The Jackson Laboratory