Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RAB12
  • Mouse genes Rab12
  • Rat genes Rab12
  • Zfish genes rab12
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Rab12

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019003	GDP binding	RAB12	IDA		Human	PMID:20937701
Molecular Function	GO:0005515	protein binding	RAB12	IPI	UniProtKB:Q5S007	Human	PMID:26824392
Cellular Component	GO:0005776	autophagosome	Rab12	IDA		Mouse	MGI:MGI:5574288|PMID:23357852
Cellular Component	GO:0005764	lysosome	Rab12	IDA		Mouse	MGI:MGI:5448516|PMID:21718402
Cellular Component	GO:0045335	phagocytic vesicle	Rab12	IDA		Mouse	PMID:19144319
Cellular Component	GO:0055038	recycling endosome membrane	Rab12	IDA		Mouse	MGI:MGI:5448516|PMID:21718402
Cellular Component	GO:0030141	secretory granule	Rab12	IDA		Rat	PMID:8575079|RGD:734515
Biological Process	GO:0071346	cellular response to type II interferon	Rab12	IDA		Mouse	PMID:19144319
Biological Process	GO:0008333	endosome to lysosome transport	Rab12	IMP		Mouse	MGI:MGI:5448516|PMID:21718402
Biological Process	GO:0016239	positive regulation of macroautophagy	Rab12	IMP		Mouse	MGI:MGI:5574288|PMID:23357852
Biological Process	GO:0030163	protein catabolic process	Rab12	IMP		Mouse	MGI:MGI:5448516|PMID:21718402

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern