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Rab12
Gene Detail
 Symbol
Name
ID
Rab12
RAB12, member RAS oncogene family
MGI:894284
Synonyms 2900054P15Rik
Feature Type protein coding gene
Genetic Map
Chromosome 17
37.88 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr17:66494512-66519717 bp, - strand
From VEGA annotation of GRCm38

  25206 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:103879  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: Ras-related protein Rab
Gene Tree: Rab12

Human
homologs
Human Homolog RAB12, RAB12, member RAS oncogene family
NCBI Gene ID 201475
neXtProt AC  NX_Q6IQ22
Human Chr (Location)  18p11.22; chr18:8609445-8639383 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(11) : Gene trapped(11)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Rab12 interacts with 221 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (20 annotations)
Process cellular protein catabolic process, endosome to lysosome transport, ...
Component autophagic vacuole, cell, ...
Function GDP binding, GTP binding, ...
External Resources: FuncBase
Expression
cDNA source data(67)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(68) cDNA(67) Other(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000021023 (Evidence)
Ensembl Gene ModelENSMUSG00000023460 (Evidence)
Entrez Gene19328 (Evidence)
UniGene248313
DFCITC1583087, TC1599203, TC1606616, TC1610918
DoTSDT.101254766, DT.101364950, DT.534599
NIA Mouse Gene IndexU038018
Consensus CDS ProjectCCDS50169.1
International Mouse Knockout Project StatusRab12
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021023 VEGA Gene Model | MGI Sequence Detail 25206 C57BL/6J ±  kb
transcript OTTMUST00000049704 VEGA | MGI Sequence Detail 2057 Not Applicable 
polypeptide OTTMUSP00000023081 VEGA | MGI Sequence Detail 291 Not Applicable 

For the selected sequences
All sequences(47) RefSeq(6) UniProt(2)
Polymorphisms SNPs within 2kb(5 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR003579 Small GTPase superfamily, Rab type
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000014380 ras-related protein Rab-12
References (Earliest) J:24144 Chavrier P, et al., The complexity of the Rab and Rho GTP-binding protein subfamilies revealed by a PCR cloning approach. Gene. 1992 Mar 15;112(2):261-4
(Latest) J:211234 Sirohi K, et al., M98K-OPTN induces transferrin receptor degradation and RAB12-mediated autophagic death in retinal ganglion cells. Autophagy. 2013 Apr;9(4):510-27
All references(38)
Other
accession IDs
MGI:1920280, MGI:2147089, MGI:2147118

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory