Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PYY,PYY3
  • Mouse genes Pyy
  • Rat genes Pyy
  • Zfish genes pyya,pyyb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pyy

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001664	G protein-coupled receptor binding	PYY	IPI	UniProtKB:P50391	Human	PMID:7493937
Molecular Function	GO:0001664	G protein-coupled receptor binding	PYY	IPI	UniProtKB:P50391	Human	PMID:7592911
Molecular Function	GO:0005184	neuropeptide hormone activity	Pyy	IDA		Mouse	PMID:15374756
Molecular Function	GO:0031841	neuropeptide Y receptor binding	pyya	IDA		Zfish	PMID:23508731
Molecular Function	GO:0005515	protein binding	PYY	IPI	UniProtKB:P25929	Human	PMID:23597562
Molecular Function	GO:0005515	protein binding	PYY	IPI	UniProtKB:P49146	Human	PMID:23597562
Molecular Function	GO:0005515	protein binding	pyya	IPI	ZFIN:ZDB-GENE-040924-8	Zfish	PMID:16257457
Molecular Function	GO:0031843	type 2 neuropeptide Y receptor binding	pyyb	IPI	UniProtKB:Q1ACB0	Zfish	PMID:16359756
Molecular Function	GO:0031843	type 2 neuropeptide Y receptor binding	pyyb	IPI	UniProtKB:Q1ACB1	Zfish	PMID:16359756
Molecular Function	GO:0031843	type 2 neuropeptide Y receptor binding	pyya	IPI	UniProtKB:Q1ACB1	Zfish	PMID:16359756
Molecular Function	GO:0031843	type 2 neuropeptide Y receptor binding	pyya	IDA		Zfish	PMID:16257457
Molecular Function	GO:0031843	type 2 neuropeptide Y receptor binding	pyya	IPI	UniProtKB:Q1ACB0	Zfish	PMID:16359756
Molecular Function	GO:0031844	type 4 neuropeptide Y receptor binding	pyyb	IDA		Zfish	PMID:23508731
Cellular Component	GO:0005615	extracellular space	Pyy	IDA		Mouse	PMID:17693256
Cellular Component	GO:0005615	extracellular space	Pyy	IDA		Rat	PMID:17065340|RGD:1624395
Biological Process	GO:0042755	eating behavior	Pyy	IDA		Mouse	PMID:15374756
Biological Process	GO:0032096	negative regulation of response to food	Pyy	IDA		Rat	PMID:17065340|RGD:1624395

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern