Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Pygl

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes PYGL
- Mouse genes Pygl
- Rat genes Pygl
- Zfish genes pygl
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pygl

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016208	AMP binding	PYGL	IDA		Human	PMID:10949035
Molecular Function	GO:0016208	AMP binding	PYGL	IDA		Human	PMID:10980448
Molecular Function	GO:0005524	ATP binding	PYGL	IDA		Human	PMID:10949035
Molecular Function	GO:0032052	bile acid binding	PYGL	IDA		Human	PMID:12204691
Molecular Function	GO:0030246	carbohydrate binding	Pygl	IDA		Rat	PMID:15152027\|RGD:1642805
Molecular Function	GO:0030246	carbohydrate binding	Pygl	IDA		Rat	PMID:6449198\|RGD:1642743
Molecular Function	GO:0005536	glucose binding	PYGL	IDA		Human	PMID:10980448
Molecular Function	GO:0005536	glucose binding	PYGL	IDA		Human	PMID:12204691
Molecular Function	GO:0008184	glycogen phosphorylase activity	PYGL	IMP		Human	PMID:10980448
Molecular Function	GO:0008184	glycogen phosphorylase activity	PYGL	IMP		Human	PMID:17705025
Molecular Function	GO:0008184	glycogen phosphorylase activity	PYGL	IDA		Human	PMID:22225877
Molecular Function	GO:0008184	glycogen phosphorylase activity	PYGL	IMP		Human	PMID:9529348
Molecular Function	GO:0008184	glycogen phosphorylase activity	Pygl	IDA		Mouse	PMID:34673295
Molecular Function	GO:0008184	glycogen phosphorylase activity	Pygl	IDA		Rat	PMID:114169\|RGD:2304128
Molecular Function	GO:0008184	glycogen phosphorylase activity	Pygl	IDA		Rat	PMID:15138155\|RGD:1582633
Molecular Function	GO:0008184	glycogen phosphorylase activity	Pygl	IDA		Rat	PMID:15152027\|RGD:1642805
Molecular Function	GO:0008184	glycogen phosphorylase activity	Pygl	IDA		Rat	PMID:1554349\|RGD:2304136
Molecular Function	GO:0008184	glycogen phosphorylase activity	Pygl	IMP		Rat	PMID:15571236\|RGD:1599376
Molecular Function	GO:0008184	glycogen phosphorylase activity	Pygl	IDA		Rat	PMID:16125296\|RGD:1601233
Molecular Function	GO:0008184	glycogen phosphorylase activity	Pygl	IDA		Rat	PMID:1733780\|RGD:2304117
Molecular Function	GO:0008184	glycogen phosphorylase activity	Pygl	IDA		Rat	PMID:2803260\|RGD:2304115
Molecular Function	GO:0008184	glycogen phosphorylase activity	Pygl	IDA		Rat	PMID:6096366\|RGD:2304113
Molecular Function	GO:0008184	glycogen phosphorylase activity	Pygl	IDA		Rat	PMID:6449198\|RGD:1642743
Molecular Function	GO:0008184	glycogen phosphorylase activity	Pygl	IDA		Rat	PMID:8550381\|RGD:2304119
Molecular Function	GO:0042802	identical protein binding	PYGL	IPI	UniProtKB:P06737	Human	PMID:10980448
Molecular Function	GO:0042802	identical protein binding	Pygl	IPI	RGD:620687	Rat	PMID:1554349\|RGD:2304136
Molecular Function	GO:0005515	protein binding	PYGL	IPI	UniProtKB:P11216	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PYGL	IPI	UniProtKB:P11216	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	PYGL	IPI	UniProtKB:P11216	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PYGL	IPI	UniProtKB:P11217	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Pygl	IPI	PR:Q9QZL0	Mouse	PMID:19498109
Molecular Function	GO:0002060	purine nucleobase binding	PYGL	IDA		Human	PMID:12204691
Molecular Function	GO:0019842	vitamin binding	PYGL	IDA		Human	PMID:12204691
Cellular Component	GO:0005737	cytoplasm	Pygl	IDA		Rat	PMID:8550381\|RGD:2304119
Cellular Component	GO:0070062	extracellular exosome	PYGL	HDA		Human	PMID:23533145
Biological Process	GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process	Pygl	IMP		Rat	PMID:15571236\|RGD:1599376
Biological Process	GO:0042593	glucose homeostasis	PYGL	IMP		Human	PMID:17705025
Biological Process	GO:0005980	glycogen catabolic process	Pygl	IMP	MGI:MGI:4362669	Mouse	PMID:31701076
Biological Process	GO:0005980	glycogen catabolic process	Pygl	IDA		Rat	PMID:114169\|RGD:2304128
Biological Process	GO:0005980	glycogen catabolic process	Pygl	IDA		Rat	PMID:15152027\|RGD:1642805
Biological Process	GO:0005980	glycogen catabolic process	Pygl	IDA		Rat	PMID:6449198\|RGD:1642743
Biological Process	GO:0005977	glycogen metabolic process	PYGL	IMP		Human	PMID:10980448
Biological Process	GO:0005977	glycogen metabolic process	PYGL	IMP		Human	PMID:17705025
Biological Process	GO:0005977	glycogen metabolic process	Pygl	IDA		Rat	PMID:1554349\|RGD:2304136
Biological Process	GO:0005977	glycogen metabolic process	Pygl	IDA		Rat	PMID:16125296\|RGD:1601233
Biological Process	GO:0005977	glycogen metabolic process	Pygl	IDA		Rat	PMID:1733780\|RGD:2304117
Biological Process	GO:0005977	glycogen metabolic process	Pygl	IDA		Rat	PMID:2803260\|RGD:2304115
Biological Process	GO:0005977	glycogen metabolic process	Pygl	IDA		Rat	PMID:6096366\|RGD:2304113
Biological Process	GO:0005977	glycogen metabolic process	Pygl	IDA		Rat	PMID:8550381\|RGD:2304119
Biological Process	GO:0070266	necroptotic process	Pygl	IGI	MGI:MGI:2154952	Mouse	PMID:19498109
Biological Process	GO:0009617	response to bacterium	Pygl	IEP		Mouse	PMID:23012479

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/25/2025 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.