About   Help   FAQ
Pygl Gene Detail
Summary
  • Symbol
    Pygl
  • Name
    liver glycogen phosphorylase
  • Feature Type
    protein coding gene
  • IDs
    MGI:97829
    NCBI Gene: 110095
Location & Maps
more
  • Sequence Map
    Chr12:70190811-70231488 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      40678 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    PYGL, phosphorylase, glycogen, liver
  • Vertebrate Orthologs
    9
  • Human Ortholog
    PYGL, phosphorylase, glycogen, liver
    Orthology source: HGNC, HomoloGene
  • Synonyms
    GSD6
  • Links
    NCBI Gene ID: 5836
    neXtProt AC: NX_P06737

  • Chr Location
    14q21-q22; chr14:50905217-50944530 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human PYGL associations

Human Disease Mouse Models
       Glycogen Storage Disease VI; GSD6   OMIM: 232700
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    2
  • Chemically induced (other)
    1
  • Targeted
    1
  • Genomic Mutations
    1 involving Pygl
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000025904 VEGA Gene Model | MGI Sequence Detail 40678 C57BL/6J ±  kb
transcript OTTMUST00000063841 VEGA | MGI Sequence Detail 2825 Not Applicable  
polypeptide OTTMUSP00000031636 VEGA | MGI Sequence Detail 850 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    381 from dbSNP Build 137
  • RFLP
Protein
Information
less
  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000013521 glycogen phosphorylase, liver form
  • EC
  • InterPro Domains
    IPR011833 Glycogen/starch/alpha-glucan phosphorylase
    IPR000811 Glycosyl transferase, family 35
Molecular
Reagents
less
  • All nucleic 12
    cDNA 10
    Primer pair 2

    Microarray probesets 2
Other
Accession IDs
less
MGD-MRK-13702
References
more
  • Summaries
    All 32
    Developmental Gene Expression 6
    Gene Ontology 9
    Phenotypes 4
  • Earliest
    J:9387 Aldrich CJ, et al., Regulation of Qa-1 expression and determinant modification by an H-2D-linked gene, Qdm. Immunogenetics. 1988;28(5):334-44
  • Latest
    J:193325 Boj SF, et al., Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand. Cell. 2012 Dec 21;151(7):1595-607

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/02/2016
MGI 6.02
The Jackson Laboratory