Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PTMA
  • Mouse genes Ptma
  • Rat genes LOC100359583,LOC689166,Ptma
  • Zfish genes ptmaa
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ptma

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0140297	DNA-binding transcription factor binding	PTMA	IPI	UniProtKB:Q92793	Human	PMID:11897665
Molecular Function	GO:0042393	histone binding	Ptma	IDA		Mouse	PMID:20434447
Molecular Function	GO:0140713	histone chaperone activity	Ptma	IDA		Mouse	PMID:20434447
Molecular Function	GO:0140713	histone chaperone activity	Ptma	IMP		Mouse	PMID:20434447
Molecular Function	GO:0043167	ion binding	PTMA	EXP		Human	PMID:34439840
Molecular Function	GO:0005515	protein binding	PTMA	IPI	UniProtKB:P27958:PRO_0000037576	Human	PMID:15607035
Molecular Function	GO:0005515	protein binding	PTMA	IPI	UniProtKB:O60356	Human	PMID:16478804
Molecular Function	GO:0005515	protein binding	PTMA	IPI	UniProtKB:Q9NYB0	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	PTMA	IPI	UniProtKB:P0DOE7	Human	PMID:25556234
Cellular Component	GO:0005829	cytosol	PTMA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	PTMA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	PTMA	IDA		Human	PMID:11897665
Cellular Component	GO:0005634	nucleus	PTMA	IDA		Human	PMID:8485135
Biological Process	GO:0006325	chromatin organization	Ptma	IDA		Mouse	PMID:20434447
Biological Process	GO:0006325	chromatin organization	Ptma	IMP		Mouse	PMID:20434447
Biological Process	GO:0043066	negative regulation of apoptotic process	PTMA	IMP		Human	PMID:16478804
Biological Process	GO:0043066	negative regulation of apoptotic process	Ptma	IDA		Rat	PMID:12522243|RGD:734494
Biological Process	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	Ptma	IDA		Rat	PMID:12522243|RGD:734494
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	LOC100359583	IGI	UniProtKB:Q92793	Rat	PMID:11897665|RGD:10059606
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	Ptma	IGI	UniProtKB:Q92793	Rat	PMID:11897665|RGD:10059606
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ptma	IDA		Rat	PMID:11897665|RGD:10059606

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern