Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PTH2R
  • Mouse genes Pth2r
  • Rat genes Pth2r
  • Zfish genes pth2ra,pth2rb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pth2r

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004991	parathyroid hormone receptor activity	Pth2r	IDA		Rat	PMID:11602681|RGD:737643
Molecular Function	GO:0004991	parathyroid hormone receptor activity	pth2ra	IDA		Zfish	PMID:10965877
Molecular Function	GO:0001653	peptide receptor activity	pth2ra	IDA		Zfish	PMID:15297442
Molecular Function	GO:0005515	protein binding	PTH2R	IPI	UniProtKB:Q9NP66	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PTH2R	IPI	UniProtKB:P63172	Human	PMID:32296183
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	pth2ra	IDA		Zfish	PMID:15297442
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	pth2ra	IDA		Zfish	PMID:10965877|ZFIN:ZDB-PUB-000831-4
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	Pth2r	IMP		Mouse	MGI:MGI:6093828|PMID:22159128

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern