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Pth2r Gene Detail
Summary
  • Symbol
    Pth2r
  • Name
    parathyroid hormone 2 receptor
  • Synonyms
    Pthr2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2180917
    NCBI Gene: 213527
  • Gene Overview
    MyGene.info: PTH2R
Location & Maps
more
  • Sequence Map
    Chr1:65282056-65389244 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      107189 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 33.05 cM, cytoband C3
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    PTH2R, parathyroid hormone 2 receptor
  • Vertebrate Orthologs
    10
  • Human Ortholog
    PTH2R, parathyroid hormone 2 receptor
    Orthology source: HomoloGene, HGNC
  • Synonyms
    PTHR2
  • Links
    NCBI Gene ID: 5746
    neXtProt AC: NX_P49190

  • Chr Location
    2q33; chr2:208359845-208494506 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    11 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Radiation induced
    1
  • Targeted
    4
  • Genomic Mutations
    2 involving Pth2r
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022339 VEGA Gene Model | MGI Sequence Detail 107189 C57BL/6J ±  kb
transcript OTTMUST00000053272 VEGA | MGI Sequence Detail 2414 Not Applicable  
polypeptide OTTMUSP00000025324 VEGA | MGI Sequence Detail 546 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    476 from dbSNP Build 142
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000013432 parathyroid hormone 2 receptor
  • InterPro Domains
    IPR001879 GPCR, family 2, extracellular hormone receptor domain
    IPR017981 GPCR, family 2-like
    IPR000832 GPCR, family 2, secretin-like
    IPR017983 GPCR, family 2, secretin-like, conserved site
Molecular
Reagents
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  • All nucleic 4
    cDNA 3
    Other 1

    Microarray probesets 2
References
more
  • Summaries
    All 28
    Gene Ontology 3
    Phenotypes 11
  • Earliest
    J:70827 Ehringer MA, et al., High-throughput sequence identification of gene coding variants within alcohol-related QTLs. Mamm Genome. 2001 Aug;12(8):657-63
  • Latest
    J:233603 Sato E, et al., The Parathyroid Hormone Second Receptor PTH2R and its Ligand Tuberoinfundibular Peptide of 39 Residues TIP39 Regulate Intracellular Calcium and Influence Keratinocyte Differentiation. J Invest Dermatol. 2016 Jul;136(7):1449-59

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/13/2016
MGI 6.05
The Jackson Laboratory