Pth2r
Gene Detail

Symbol Name ID

Pth2r parathyroid hormone 2 receptor MGI:2180917

Synonyms

Pthr2

Feature Type

protein coding gene

Genetic Map

Chromosome 1

33.05 cM, cytoband C3
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr1:65282056-65389244 bp, + strand From VEGA annotation of GRCm38   107189 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:3701  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 2 zebrafish

Protein SuperFamily: G protein-coupled receptor, peptide hormone receptor type
Gene Tree: Pth2r

Human homologs

Human Homolog		PTH2R, parathyroid hormone 2 receptor
NCBI Gene ID		5746
neXtProt AC		NX_P49190
Human Synonyms		PTHR2
Human Chr (Location)		2q33; chr2:209271556-209359231 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(4) : Targeted(4)

Gene Ontology (GO) classifications

All GO classifications: (14 annotations)

Process	cell surface receptor signaling pathway, G-protein coupled receptor signaling pathway, ...
Component	integral to membrane, membrane, ...
Function	G-protein coupled receptor activity, parathyroid hormone receptor activity, ...

External Resources: FuncBase

Expression

cDNA source data(3)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(4) cDNA(3) Other(1)
Microarray probesets(2)

Other database links

VEGA Gene Model	OTTMUSG00000022339 (Evidence)
Ensembl Gene Model	ENSMUSG00000025946 (Evidence)
Entrez Gene	213527 (Evidence)
DFCI	TC1589626, TC1664600
DoTS	DT.87034857
NIA Mouse Gene Index	U000385
Consensus CDS Project	CCDS15017.1
International Mouse Knockout Project Status	Pth2r

Sequences

Length	Strain/Species
genomic	OTTMUSG00000022339	VEGA Gene Model | MGI Sequence Detail	107189	C57BL/6J
transcript	OTTMUST00000053272	VEGA | MGI Sequence Detail	2414	Not Applicable
polypeptide	OTTMUSP00000025324	VEGA | MGI Sequence Detail	546	Not Applicable

All sequences(28) RefSeq(2) UniProt(4)

Polymorphisms

SNPs within 2kb(497 from dbSNP Build 137)    SNPs within 2kb including multiple locations(511)

Protein-related information

Resource	ID	Description
InterPro	IPR001879	GPCR, family 2, extracellular hormone receptor domain
InterPro	IPR017981	GPCR, family 2-like
InterPro	IPR000832	GPCR, family 2, secretin-like
InterPro	IPR017983	GPCR, family 2, secretin-like, conserved site
Protein Ontology	PR:000013432	parathyroid hormone 2 receptor

References

(Earliest) J:70827 Ehringer MA, et al., High-throughput sequence identification of gene coding variants within alcohol-related QTLs. Mamm Genome. 2001 Aug;12(8):657-63
(Latest) J:189802 Atchison DK, et al., Parathyroid hormone stimulates juxtaglomerular cell cAMP accumulation without stimulating renin release. Am J Physiol Renal Physiol. 2012 Oct 15;303(8):F1157-65
All references(30)