Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PSMC2
  • Mouse genes Psmc2
  • Rat genes Psmc2
  • Zfish genes psmc2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Psmc2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0140296	general transcription initiation factor binding	Psmc2	IPI	RGD:1359646	Rat	PMID:11118327|RGD:9681443
Molecular Function	GO:0036402	proteasome-activating activity	PSMC2	IDA		Human	PMID:9295362
Molecular Function	GO:0005515	protein binding	PSMC2	IPI	UniProtKB:Q16401	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	PSMC2	IPI	UniProtKB:P62195	Human	PMID:16763564
Molecular Function	GO:0005515	protein binding	PSMC2	IPI	UniProtKB:P62191	Human	PMID:19490896
Molecular Function	GO:0005515	protein binding	PSMC2	IPI	UniProtKB:P62195	Human	PMID:19490896
Molecular Function	GO:0005515	protein binding	PSMC2	IPI	UniProtKB:Q16401	Human	PMID:19490896
Molecular Function	GO:0005515	protein binding	PSMC2	IPI	UniProtKB:Q16401	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	PSMC2	IPI	UniProtKB:Q0PF16	Human	PMID:22078707
Molecular Function	GO:0005515	protein binding	PSMC2	IPI	UniProtKB:Q9C035	Human	PMID:22078707
Molecular Function	GO:0005515	protein binding	PSMC2	IPI	UniProtKB:P62191	Human	PMID:22901813
Molecular Function	GO:0005515	protein binding	PSMC2	IPI	UniProtKB:P62195	Human	PMID:22901813
Molecular Function	GO:0005515	protein binding	PSMC2	IPI	UniProtKB:Q13200	Human	PMID:22901813
Molecular Function	GO:0005515	protein binding	PSMC2	IPI	UniProtKB:Q16401	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PSMC2	IPI	UniProtKB:P62191	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	PSMC2	IPI	UniProtKB:Q16401	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	PSMC2	IPI	UniProtKB:P62191	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PSMC2	IPI	UniProtKB:P62195	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PSMC2	IPI	UniProtKB:Q16401	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PSMC2	IPI	UniProtKB:Q16401	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	PSMC2	IPI	UniProtKB:Q13200	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PSMC2	IPI	UniProtKB:Q16401	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PSMC2	IPI	UniProtKB:O14901	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PSMC2	IPI	UniProtKB:Q96CV9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PSMC2	IPI	UniProtKB:Q9BVL2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Psmc2	IPI	UniProtKB:Q0PF16	Mouse	MGI:MGI:5487513|PMID:22078707
Molecular Function	GO:0005515	protein binding	Psmc2	IPI	PR:P42859	Mouse	PMID:17500595
Molecular Function	GO:0017025	TBP-class protein binding	Psmc2	IPI	RGD:68981	Rat	PMID:10526239|RGD:6771232
Cellular Component	GO:0036464	cytoplasmic ribonucleoprotein granule	PSMC2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	PSMC2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043197	dendritic spine	Psmc2	IDA		Rat	PMID:16810255|RGD:12050100
Cellular Component	GO:0016020	membrane	PSMC2	HDA		Human	PMID:16210410
Cellular Component	GO:0016020	membrane	PSMC2	HDA		Human	PMID:19946888
Cellular Component	GO:0005634	nucleus	PSMC2	HDA		Human	PMID:21630459
Cellular Component	GO:0005634	nucleus	Psmc2	IDA		Rat	PMID:10526239|RGD:6771232
Cellular Component	GO:0000932	P-body	Psmc2	IDA		Mouse	MGI:MGI:5487513|PMID:22078707
Cellular Component	GO:0022624	proteasome accessory complex	Psmc2	IDA		Mouse	MGI:MGI:5442509|PMID:16857966
Cellular Component	GO:0000502	proteasome complex	PSMC2	IDA		Human	PMID:17323924
Cellular Component	GO:0000502	proteasome complex	PSMC2	IDA		Human	PMID:9295362
Cellular Component	GO:0000502	proteasome complex	PSMC2	IDA		Human	PMID:9464850
Biological Process	GO:0001649	osteoblast differentiation	PSMC2	HDA		Human	PMID:16210410
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	PSMC2	IDA		Human	PMID:9295362

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern