Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PRSS8
  • Mouse genes Prss8
  • Rat genes Prss8
  • Zfish genes zgc:92313
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prss8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PRSS8	IPI	UniProtKB:P07093	Human	PMID:19911255
Molecular Function	GO:0017080	sodium channel regulator activity	Prss8	IMP		Mouse	MGI:MGI:3703397|PMID:16822939
Cellular Component	GO:0070062	extracellular exosome	PRSS8	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	PRSS8	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	PRSS8	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	PRSS8	HDA		Human	PMID:16502470
Cellular Component	GO:0005615	extracellular space	Prss8	IDA		Mouse	MGI:MGI:3703397|PMID:16822939
Cellular Component	GO:0005615	extracellular space	Prss8	IDA		Rat	PMID:12506133|RGD:2292493
Cellular Component	GO:0019897	extrinsic component of plasma membrane	Prss8	IDA		Mouse	MGI:MGI:3703397|PMID:16822939
Cellular Component	GO:0045121	membrane raft	Prss8	IDA		Mouse	MGI:MGI:3703397|PMID:16822939
Cellular Component	GO:0005886	plasma membrane	PRSS8	IDA		Human	PMID:19911255
Cellular Component	GO:0005886	plasma membrane	Prss8	IDA		Mouse	MGI:MGI:3703397|PMID:16822939
Biological Process	GO:0001942	hair follicle development	Prss8	IMP	MGI:MGI:1856875	Mouse	MGI:MGI:48632
Biological Process	GO:1902307	positive regulation of sodium ion transmembrane transport	Prss8	IDA		Rat	PMID:11373334|RGD:727316
Biological Process	GO:0010765	positive regulation of sodium ion transport	Prss8	IGI	MGI:MGI:104695	Mouse	PMID:16941024
Biological Process	GO:0010765	positive regulation of sodium ion transport	Prss8	IGI	MGI:MGI:104696	Mouse	PMID:16941024
Biological Process	GO:0010765	positive regulation of sodium ion transport	Prss8	IGI	MGI:MGI:101782	Mouse	PMID:16941024
Biological Process	GO:0051385	response to mineralocorticoid	Prss8	IEP		Rat	PMID:17468916|RGD:2292488
Biological Process	GO:0043434	response to peptide hormone	Prss8	IEP		Rat	PMID:16528252|RGD:2292490
Biological Process	GO:0009410	response to xenobiotic stimulus	Prss8	IEP		Rat	PMID:12506133|RGD:2292493
Biological Process	GO:0070633	transepithelial transport	Prss8	IMP		Mouse	MGI:MGI:3703397|PMID:16822939

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern