Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PRR5L
  • Mouse genes Prr5l
  • Rat genes Prr5l
  • Zfish genes prr5l
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Prr5l

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PRR5L	IPI	UniProtKB:P26651	Human	PMID:21964062
Molecular Function	GO:0005515	protein binding	PRR5L	IPI	UniProtKB:Q6R327	Human	PMID:21964062
Molecular Function	GO:0005515	protein binding	PRR5L	IPI	UniProtKB:O75031	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRR5L	IPI	UniProtKB:O75604	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRR5L	IPI	UniProtKB:P40692	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRR5L	IPI	UniProtKB:Q13643	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRR5L	IPI	UniProtKB:Q14192	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRR5L	IPI	UniProtKB:Q5JVL4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRR5L	IPI	UniProtKB:Q63ZY3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRR5L	IPI	UniProtKB:Q6PF18	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRR5L	IPI	UniProtKB:Q7Z6B0-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRR5L	IPI	UniProtKB:Q8IVT2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRR5L	IPI	UniProtKB:Q9BSU1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRR5L	IPI	UniProtKB:Q9BWG6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRR5L	IPI	UniProtKB:Q9H0C1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PRR5L	IPI	UniProtKB:Q9UI95	Human	PMID:32296183
Molecular Function	GO:0031625	ubiquitin protein ligase binding	PRR5L	IPI	UniProtKB:Q8WZ73	Human	PMID:22609986
Cellular Component	GO:0005739	mitochondrion	Prr5l	HDA		Mouse	PMID:18614015
Cellular Component	GO:0031932	TORC2 complex	PRR5L	IDA		Human	PMID:22609986
Biological Process	GO:0034599	cellular response to oxidative stress	PRR5L	IMP		Human	PMID:21964062
Biological Process	GO:0001933	negative regulation of protein phosphorylation	PRR5L	IMP		Human	PMID:22609986
Biological Process	GO:0014065	phosphatidylinositol 3-kinase signaling	Prr5l	IGI	MGI:MGI:1924714	Mouse	PMID:21413931
Biological Process	GO:0090316	positive regulation of intracellular protein transport	PRR5L	IMP		Human	PMID:21964062
Biological Process	GO:0061014	positive regulation of mRNA catabolic process	PRR5L	IMP		Human	PMID:21964062
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	Prr5l	IGI	MGI:MGI:1924714	Mouse	PMID:21413931
Biological Process	GO:0001934	positive regulation of protein phosphorylation	Prr5l	IGI	MGI:MGI:1924714	Mouse	PMID:21413931
Biological Process	GO:0006468	protein phosphorylation	Prr5l	IGI	MGI:MGI:1924714	Mouse	PMID:21413931
Biological Process	GO:0010762	regulation of fibroblast migration	PRR5L	IMP		Human	PMID:22609986
Biological Process	GO:0010762	regulation of fibroblast migration	Prr5l	IMP		Mouse	MGI:MGI:5448916|PMID:22609986
Biological Process	GO:0038203	TORC2 signaling	PRR5L	IDA		Human	PMID:22609986
Biological Process	GO:0038203	TORC2 signaling	Prr5l	IMP		Mouse	MGI:MGI:5448916|PMID:22609986

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern