Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PPP3CC
  • Mouse genes Ppp3cc
  • Rat genes Ppp3cc
  • Zfish genes ppp3cca,ppp3ccb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ppp3cc

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	PPP3CC	IDA		Human	PMID:26429887
Molecular Function	GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	Ppp3cc	IDA		Mouse	PMID:26429887
Molecular Function	GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	Ppp3cc	IMP	MGI:MGI:5788175	Mouse	PMID:26429887
Molecular Function	GO:0033192	calmodulin-dependent protein phosphatase activity	PPP3CC	IDA		Human	PMID:19154138
Molecular Function	GO:0005515	protein binding	PPP3CC	IPI	UniProtKB:P49418	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PPP3CC	IPI	UniProtKB:P63098	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PPP3CC	IPI	UniProtKB:P63098	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PPP3CC	IPI	UniProtKB:Q13432	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PPP3CC	IPI	UniProtKB:Q96N06	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PPP3CC	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PPP3CC	IPI	UniProtKB:Q96N06	Human	PMID:34446558
Molecular Function	GO:0005515	protein binding	Ppp3cc	IPI	UniProtKB:Q9Z2R6	Mouse	MGI:MGI:6383261|PMID:31696965
Molecular Function	GO:0005515	protein binding	Ppp3cc	IPI	PR:Q8C624	Mouse	PMID:34446558
Molecular Function	GO:0005515	protein binding	Ppp3cc	IPI	RGD:620103	Rat	PMID:15120593|RGD:1579942
Cellular Component	GO:0005955	calcineurin complex	Ppp3cc	IDA		Mouse	PMID:1325794
Cellular Component	GO:0005955	calcineurin complex	Ppp3cc	IDA		Mouse	PMID:26429887
Cellular Component	GO:0005955	calcineurin complex	Ppp3cc	IGI	MGI:MGI:107171	Mouse	PMID:26429887
Cellular Component	GO:0005737	cytoplasm	PPP3CC	IDA		Human	PMID:19154138
Cellular Component	GO:0098978	glutamatergic synapse	Ppp3cc	IDA		Mouse	PMID:26627835
Cellular Component	GO:0098978	glutamatergic synapse	Ppp3cc	IDA		Rat	PMID:26627835|RGD:11532172
Cellular Component	GO:0098978	glutamatergic synapse	Ppp3cc	IMP		Rat	PMID:26627835|RGD:11532172
Cellular Component	GO:0005739	mitochondrion	Ppp3cc	IDA		Mouse	MGI:MGI:6758705|PMID:34446558
Cellular Component	GO:0098793	presynapse	Ppp3cc	IDA		Rat	PMID:26627835|RGD:11532172
Cellular Component	GO:0099523	presynaptic cytosol	Ppp3cc	IDA		Mouse	PMID:26627835
Cellular Component	GO:0036126	sperm flagellum	Ppp3cc	IDA		Mouse	PMID:26429887
Cellular Component	GO:0097225	sperm midpiece	Ppp3cc	IDA		Mouse	MGI:MGI:6758705|PMID:34446558
Cellular Component	GO:0097226	sperm mitochondrial sheath	Ppp3cc	IDA		Mouse	PMID:34446558
Biological Process	GO:0007420	brain development	Ppp3cc	IEP		Rat	PMID:16367768|RGD:1580674
Biological Process	GO:0033173	calcineurin-NFAT signaling cascade	PPP3CC	IDA		Human	PMID:19154138
Biological Process	GO:0007341	penetration of zona pellucida	Ppp3cc	IMP	MGI:MGI:5788175	Mouse	PMID:26429887
Biological Process	GO:1900244	positive regulation of synaptic vesicle endocytosis	Ppp3cc	IMP		Rat	PMID:26627835|RGD:11532172
Biological Process	GO:0006470	protein dephosphorylation	PPP3CC	IDA		Human	PMID:19154138
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	Ppp3cc	IDA		Rat	PMID:26627835|RGD:11532172
Biological Process	GO:1900242	regulation of synaptic vesicle endocytosis	Ppp3cc	IMP		Rat	PMID:26627835|RGD:11532172

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern