Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PPM1F
  • Mouse genes Ppm1f
  • Rat genes Ppm1f
  • Zfish genes ppm1f
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ppm1f

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0033192	calmodulin-dependent protein phosphatase activity	PPM1F	IDA		Human	PMID:11559703
Molecular Function	GO:0033192	calmodulin-dependent protein phosphatase activity	PPM1F	IDA		Human	PMID:15140879
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	Ppm1f	IDA		Rat	PMID:16844074|RGD:7241141
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	ppm1f	IDA		Zfish	PMID:19527677
Molecular Function	GO:0005515	protein binding	PPM1F	IPI	UniProtKB:P17221	Human	PMID:11559703
Molecular Function	GO:0005515	protein binding	PPM1F	IPI	UniProtKB:P34691	Human	PMID:11559703
Molecular Function	GO:0005515	protein binding	PPM1F	IPI	UniProtKB:Q9UK73	Human	PMID:11559703
Molecular Function	GO:0005515	protein binding	PPM1F	IPI	UniProtKB:Q14155	Human	PMID:11864573
Molecular Function	GO:0005515	protein binding	PPM1F	IPI	UniProtKB:P11798	Human	PMID:15140879
Molecular Function	GO:0005515	protein binding	PPM1F	IPI	UniProtKB:Q8C078	Human	PMID:15140879
Molecular Function	GO:0005515	protein binding	PPM1F	IPI	UniProtKB:O60610	Human	PMID:18230650
Molecular Function	GO:0005515	protein binding	PPM1F	IPI	UniProtKB:P54646	Human	PMID:20801214
Molecular Function	GO:0005515	protein binding	PPM1F	IPI	UniProtKB:Q92845	Human	PMID:24338362
Molecular Function	GO:0005515	protein binding	PPM1F	IPI	UniProtKB:Q9Y496	Human	PMID:24338362
Molecular Function	GO:0004722	protein serine/threonine phosphatase activity	PPM1F	IDA		Human	PMID:11559703
Molecular Function	GO:0004722	protein serine/threonine phosphatase activity	PPM1F	IDA		Human	PMID:11864573
Molecular Function	GO:0004722	protein serine/threonine phosphatase activity	PPM1F	IDA		Human	PMID:15140879
Molecular Function	GO:0004722	protein serine/threonine phosphatase activity	PPM1F	IMP		Human	PMID:20016286
Molecular Function	GO:0004722	protein serine/threonine phosphatase activity	PPM1F	IDA		Human	PMID:20801214
Molecular Function	GO:0004722	protein serine/threonine phosphatase activity	Ppm1f	IDA		Rat	PMID:10456318|RGD:7241145
Molecular Function	GO:0008138	protein tyrosine/serine/threonine phosphatase activity	PPM1F	IMP		Human	PMID:24338362
Cellular Component	GO:0005829	cytosol	PPM1F	IDA		Human	PMID:11559703
Cellular Component	GO:0005829	cytosol	Ppm1f	IDA		Rat	PMID:10348902|RGD:632383
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Ppm1f	IDA		Rat	PMID:10348902|RGD:632383
Cellular Component	GO:0032991	protein-containing complex	PPM1F	IDA		Human	PMID:11864573
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	PPM1F	IDA		Human	PMID:20801214
Biological Process	GO:0097193	intrinsic apoptotic signaling pathway	PPM1F	IDA		Human	PMID:11559703
Biological Process	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin	PPM1F	IMP		Human	PMID:24338362
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	PPM1F	IMP		Human	PMID:20016286
Biological Process	GO:0033137	negative regulation of peptidyl-serine phosphorylation	PPM1F	IDA		Human	PMID:15140879
Biological Process	GO:0006469	negative regulation of protein kinase activity	PPM1F	IDA		Human	PMID:11864573
Biological Process	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation	PPM1F	IDA		Human	PMID:15140879
Biological Process	GO:0051224	negative regulation of protein transport	PPM1F	IMP		Human	PMID:24338362
Biological Process	GO:0070262	peptidyl-serine dephosphorylation	PPM1F	IMP		Human	PMID:24338362
Biological Process	GO:0035970	peptidyl-threonine dephosphorylation	PPM1F	IDA		Human	PMID:11559703
Biological Process	GO:0035970	peptidyl-threonine dephosphorylation	PPM1F	IDA		Human	PMID:11864573
Biological Process	GO:0035970	peptidyl-threonine dephosphorylation	PPM1F	IDA		Human	PMID:15140879
Biological Process	GO:0035970	peptidyl-threonine dephosphorylation	PPM1F	IDA		Human	PMID:20801214
Biological Process	GO:0030335	positive regulation of cell migration	PPM1F	IGI	RNAcentral:URS00001C770D_9606	Human	PMID:26498692
Biological Process	GO:0010811	positive regulation of cell-substrate adhesion	PPM1F	IMP		Human	PMID:20016286
Biological Process	GO:0050921	positive regulation of chemotaxis	PPM1F	IMP		Human	PMID:20016286
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	PPM1F	IDA		Human	PMID:11559703
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	Ppm1f	IDA		Rat	PMID:11559703|RGD:8553939
Biological Process	GO:0010634	positive regulation of epithelial cell migration	PPM1F	IMP		Human	PMID:20016286
Biological Process	GO:0051894	positive regulation of focal adhesion assembly	PPM1F	IMP		Human	PMID:20016286
Biological Process	GO:0010628	positive regulation of gene expression	PPM1F	IMP		Human	PMID:20016286
Biological Process	GO:0045927	positive regulation of growth	PPM1F	IMP		Human	PMID:20016286
Biological Process	GO:0051496	positive regulation of stress fiber assembly	PPM1F	IDA		Human	PMID:11864573
Biological Process	GO:0051496	positive regulation of stress fiber assembly	PPM1F	IMP		Human	PMID:20016286
Biological Process	GO:0051496	positive regulation of stress fiber assembly	PPM1F	IGI	RNAcentral:URS00001C770D_9606	Human	PMID:26498692
Biological Process	GO:0006470	protein dephosphorylation	Ppm1f	IDA		Rat	PMID:10456318|RGD:7241145
Biological Process	GO:0006470	protein dephosphorylation	ppm1f	IDA		Zfish	PMID:19527677
Biological Process	GO:0032880	regulation of protein localization	PPM1F	IMP		Human	PMID:24338362

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern