Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PON3
  • Mouse genes Pon3
  • Rat genes Pon3
  • Zfish genes pon1,pon3.1,pon3.2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pon3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0018733	3,4-dihydrocoumarin hydrolase activity	Pon3	IDA		Rat	PMID:12946270|RGD:1303961
Molecular Function	GO:0004064	arylesterase activity	PON3	IDA		Human	PMID:15772423
Molecular Function	GO:0004064	arylesterase activity	Pon3	IDA		Rat	PMID:12946270|RGD:1303961
Molecular Function	GO:0042803	protein homodimerization activity	PON3	IDA		Human	PMID:15772423
Cellular Component	GO:0070062	extracellular exosome	PON3	HDA		Human	PMID:19199708
Cellular Component	GO:0005615	extracellular space	Pon3	IDA		Rat	PMID:19091700|RGD:5509928
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	Pon3	IDA		Rat	PMID:12946270|RGD:1303961
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	Pon3	IDA		Rat	PMID:19091700|RGD:5509928
Biological Process	GO:0019439	aromatic compound catabolic process	PON3	IDA		Human	PMID:15772423
Biological Process	GO:0046395	carboxylic acid catabolic process	PON3	IDA		Human	PMID:15772423
Biological Process	GO:0046226	coumarin catabolic process	Pon3	IDA		Rat	PMID:12946270|RGD:1303961
Biological Process	GO:0051649	establishment of localization in cell	Pon3	IDA		Mouse	PMID:32079677
Biological Process	GO:0051649	establishment of localization in cell	Pon3	IPI	GO:0034706	Mouse	PMID:32079677
Biological Process	GO:0051649	establishment of localization in cell	Pon3	IMP		Mouse	PMID:32079677
Biological Process	GO:0032929	negative regulation of superoxide anion generation	Pon3	IDA		Mouse	MGI:MGI:5543365|PMID:22441669
Biological Process	GO:0010124	phenylacetate catabolic process	Pon3	IDA		Rat	PMID:12946270|RGD:1303961
Biological Process	GO:0003096	renal sodium ion transport	Pon3	IPI	GO:0034706	Mouse	PMID:32079677
Biological Process	GO:0003096	renal sodium ion transport	Pon3	IDA		Mouse	PMID:32079677
Biological Process	GO:0003096	renal sodium ion transport	Pon3	IMP		Mouse	PMID:32079677

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern