Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes POLRMT
  • Mouse genes Polrmt
  • Rat genes Polrmt
  • Zfish genes polrmt
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Polrmt

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0000175	3'-5'-RNA exonuclease activity	POLRMT	IDA		Human	PMID:35449456
Molecular Function	GO:0003896	DNA primase activity	POLRMT	IDA		Human	PMID:18685103
Molecular Function	GO:0003899	DNA-directed 5'-3' RNA polymerase activity	POLRMT	IDA		Human	PMID:21278163
Molecular Function	GO:0005515	protein binding	POLRMT	IPI	UniProtKB:P52815	Human	PMID:17337445
Molecular Function	GO:0005515	protein binding	POLRMT	IPI	UniProtKB:Q96QE5	Human	PMID:21278163
Molecular Function	GO:0005515	protein binding	POLRMT	IPI	UniProtKB:P52815	Human	PMID:22003127
Molecular Function	GO:0005515	protein binding	POLRMT	IPI	UniProtKB:O43524,UniProtKB:Q9NTG7	Human	PMID:23283301
Molecular Function	GO:0005515	protein binding	POLRMT	IPI	UniProtKB:P52815	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	POLRMT	IPI	UniProtKB:O43524,UniProtKB:Q00059,UniProtKB:Q9NTG7	Human	PMID:29445193
Molecular Function	GO:0005515	protein binding	POLRMT	IPI	UniProtKB:Q9P0P8	Human	PMID:31226201
Molecular Function	GO:0005515	protein binding	Polrmt	IPI	UniProtKB:Q8R104,UniProtKB:Q9WVH4	Mouse	MGI:MGI:6120139|PMID:23283301
Molecular Function	GO:0003723	RNA binding	POLRMT	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	POLRMT	HDA		Human	PMID:22681889
Molecular Function	GO:0043565	sequence-specific DNA binding	POLRMT	IDA		Human	PMID:29445193
Molecular Function	GO:0043565	sequence-specific DNA binding	Polrmt	IDA		Mouse	MGI:MGI:6120139|PMID:23283301
Cellular Component	GO:0005759	mitochondrial matrix	POLRMT	IDA		Human	PMID:29445193
Cellular Component	GO:0042645	mitochondrial nucleoid	POLRMT	IDA		Human	PMID:18063578
Cellular Component	GO:0005739	mitochondrion	POLRMT	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	POLRMT	IDA		Human	PMID:17337445
Cellular Component	GO:0005739	mitochondrion	Polrmt	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Polrmt	HDA		Mouse	PMID:18614015
Cellular Component	GO:0032991	protein-containing complex	POLRMT	IDA		Human	PMID:23283301
Cellular Component	GO:0032991	protein-containing complex	POLRMT	IDA		Human	PMID:29445193
Cellular Component	GO:0032991	protein-containing complex	Polrmt	IDA		Mouse	MGI:MGI:6120139|PMID:23283301
Biological Process	GO:0006390	mitochondrial transcription	POLRMT	IDA		Human	PMID:21278163
Biological Process	GO:0006391	transcription initiation at mitochondrial promoter	POLRMT	IDA		Human	PMID:29149603

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern