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Polrmt
Gene Detail
Symbol

Name
ID
Polrmt
polymerase (RNA) mitochondrial (DNA directed)
MGI:1915843
Synonyms
1110018N15Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 10
39.72 cM, cytoband C1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr10:79736123-79746581 bp, - strand
From VEGA annotation of GRCm38

  10459 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37996  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: POLRMT
Protein SuperFamily: DNA-directed RNA polymerase
Gene Tree: Polrmt

Human
homologs
POLRMT, polymerase (RNA) mitochondrial (DNA directed)
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 5442
neXtProt AC: NX_O00411

Human Synonyms: APOLMT, h-mtRPOL, MTRNAP, MTRPOL

Human Chr (Location): 19p13.3; chr19:617223-633592 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(2) Targeted(3)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Polrmt interacts with 154 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (3 records)
Data Summary: Results (100)    Tissues (100)    Images (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 95
RT-PCR 5
cDNA source data(14)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase polrmt ; ZFIN polrmt    NEW 
Molecular
reagents
All nucleic(15) cDNA(14) Primer pair(1)
Microarray probesets(8)
Other database
links
VEGA Gene Model OTTMUSG00000027870 (Evidence)
Ensembl Gene Model ENSMUSG00000020329 (Evidence)
Entrez Gene 216151 (Evidence)
DFCI TC1643901, TC1611311, TC1606612, TC1716953, TC1575063
DoTS DT.101739530, DT.101393644, DT.101153077, DT.94225019, DT.94224993, DT.110629927, DT.60101334, DT.102534361, DT.532159
NIA Mouse Gene Index U031990
EC 2.7.7.6
Consensus CDS Project CCDS23987.1
International Mouse Phenotyping Consortium Status Polrmt
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027870 VEGA Gene Model | MGI Sequence Detail 10459 C57BL/6J ±  kb
transcript OTTMUST00000068992 VEGA | MGI Sequence Detail 3755 Not Applicable 
polypeptide OTTMUSP00000034996 VEGA | MGI Sequence Detail 1207 Not Applicable 

For the selected sequences
All sequences(84) RefSeq(3) UniProt(7)
Polymorphisms
SNPs within 2kb(8 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR024075 DNA-directed RNA polymerase, helix hairpin domain
InterPro IPR002092 DNA-directed RNA polymerase, phage-type
InterPro IPR002885 Pentatricopeptide repeat
Protein Ontology PR:000013010 DNA-directed RNA polymerase, mitochondrial
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:183842 Lodeiro MF, et al., Transcription from the second heavy-strand promoter of human mtDNA is repressed by transcription factor A in vitro. Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6513-8
All references(34)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/20/2015
MGI 5.22
The Jackson Laboratory