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Polrmt Gene Detail
Summary
  • Symbol
    Polrmt
  • Name
    polymerase (RNA) mitochondrial (DNA directed)
  • Synonyms
    1110018N15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915843
    NCBI Gene: 216151
  • Gene Overview
    MyGene.info: POLRMT
Location & Maps
more
  • Sequence Map
    Chr10:79736123-79746581 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      10459 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 39.72 cM, cytoband C1
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    POLRMT, RNA polymerase mitochondrial
  • Vertebrate Orthologs
    9
  • Human Ortholog
    POLRMT, RNA polymerase mitochondrial
    Orthology source: HomoloGene, HGNC
  • Synonyms
    APOLMT, h-mtRPOL, MTRNAP, MTRPOL
  • Links
    NCBI Gene ID: 5442
    neXtProt AC: NX_O00411

  • Chr Location
    19p13.3; chr19:617223-633592 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Gene trapped
    2
  • Targeted
    4
  • Genomic Mutations
    1 involving Polrmt
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027870 VEGA Gene Model | MGI Sequence Detail 10459 C57BL/6J ±  kb
transcript OTTMUST00000068992 VEGA | MGI Sequence Detail 3755 Not Applicable  
polypeptide OTTMUSP00000034996 VEGA | MGI Sequence Detail 1207 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    8 from dbSNP Build 142
Protein
Information
less
  • UniProt
    7 Sequences
  • Protein Ontology
    PR:000013010 DNA-directed RNA polymerase, mitochondrial
  • EC
  • InterPro Domains
    IPR024075 DNA-directed RNA polymerase, helix hairpin domain
    IPR029262 DNA-directed RNA polymerase, N-terminal
    IPR002092 DNA-directed RNA polymerase, phage-type
    IPR002885 Pentatricopeptide repeat
Molecular
Reagents
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  • All nucleic 15
    cDNA 14
    Primer pair 1

    Microarray probesets 8
References
more
  • Summaries
    All 32
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:217486 Kuhl I, et al., POLRMT does not transcribe nuclear genes. Nature. 2014 Oct 9;514(7521):E7-11

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory