Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes POLR3A
  • Mouse genes Polr3a
  • Rat genes Polr3a
  • Zfish genes polr3a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Polr3a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Polr3a	IDA		Mouse	PMID:22287103
Molecular Function	GO:0005515	protein binding	POLR3A	IPI	UniProtKB:Q99959	Human	PMID:11416169
Cellular Component	GO:0016020	membrane	POLR3A	HDA		Human	PMID:19946888
Cellular Component	GO:0005654	nucleoplasm	POLR3A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	POLR3A	IDA		Human	PMID:11416169
Cellular Component	GO:0005666	RNA polymerase III complex	POLR3A	IDA		Human	PMID:24107381
Biological Process	GO:0045087	innate immune response	POLR3A	IMP		Human	PMID:19609254
Biological Process	GO:0032728	positive regulation of interferon-beta production	POLR3A	IMP		Human	PMID:19609254

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern