Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes POFUT2
  • Mouse genes Pofut2
  • Rat genes Pofut2
  • Zfish genes pofut2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pofut2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008417	fucosyltransferase activity	Pofut2	IDA		Mouse	PMID:20637190
Molecular Function	GO:0046922	peptide-O-fucosyltransferase activity	POFUT2	IDA		Human	PMID:22588082
Cellular Component	GO:0005794	Golgi apparatus	POFUT2	IDA		Human	PMID:15233996
Biological Process	GO:0036065	fucosylation	Pofut2	IMP	MGI:MGI:3604508	Mouse	PMID:20637190
Biological Process	GO:0036065	fucosylation	Pofut2	IMP	MGI:MGI:4127173	Mouse	PMID:20637190
Biological Process	GO:0001707	mesoderm formation	Pofut2	IMP	MGI:MGI:3604508	Mouse	PMID:20637190
Biological Process	GO:0001707	mesoderm formation	Pofut2	IMP	MGI:MGI:4127173	Mouse	PMID:20637190
Biological Process	GO:1903334	positive regulation of protein folding	POFUT2	IMP		Human	PMID:25544610
Biological Process	GO:0036066	protein O-linked fucosylation	POFUT2	IDA		Human	PMID:22588082
Biological Process	GO:0010717	regulation of epithelial to mesenchymal transition	Pofut2	IMP	MGI:MGI:3604508	Mouse	PMID:20637190
Biological Process	GO:0010717	regulation of epithelial to mesenchymal transition	Pofut2	IMP	MGI:MGI:4127173	Mouse	PMID:20637190
Biological Process	GO:0010468	regulation of gene expression	Pofut2	IMP	MGI:MGI:3604508	Mouse	PMID:20637190
Biological Process	GO:0010468	regulation of gene expression	Pofut2	IMP	MGI:MGI:4127173	Mouse	PMID:20637190
Biological Process	GO:0051046	regulation of secretion	POFUT2	IDA		Human	PMID:17395589

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern