Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLXNA2
  • Mouse genes Plxna2
  • Rat genes Plxna2
  • Zfish genes plxna2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Plxna2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	Plxna2	IPI	UniProtKB:P70207	Mouse	MGI:MGI:5306549|PMID:20881961
Molecular Function	GO:0042802	identical protein binding	Plxna2	IPI	UniProtKB:P70207	Mouse	MGI:MGI:5306550|PMID:20877282
Molecular Function	GO:0005515	protein binding	PLXNA2	IPI	UniProtKB:P39688	Human	PMID:12372285
Molecular Function	GO:0005515	protein binding	Plxna2	IPI	UniProtKB:O35464-1	Mouse	MGI:MGI:5306549|PMID:20881961
Molecular Function	GO:0005515	protein binding	Plxna2	IPI	UniProtKB:P97333	Mouse	MGI:MGI:5918310|PMID:23104057
Molecular Function	GO:0005515	protein binding	Plxna2	IPI	UniProtKB:O35464-1	Mouse	MGI:MGI:5306550|PMID:20877282
Molecular Function	GO:0017154	semaphorin receptor activity	Plxna2	IMP		Mouse	MGI:MGI:5306550|PMID:20877282
Molecular Function	GO:0017154	semaphorin receptor activity	Plxna2	IPI	PR:O35464	Mouse	PMID:18327254
Molecular Function	GO:0017154	semaphorin receptor activity	Plxna2	IGI	MGI:MGI:107684	Mouse	PMID:18327254
Molecular Function	GO:0017154	semaphorin receptor activity	Plxna2	IGI	MGI:MGI:1203727	Mouse	PMID:18327254
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Plxna2	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0005886	plasma membrane	Plxna2	IDA		Mouse	MGI:MGI:5306549|PMID:20881961
Biological Process	GO:0007166	cell surface receptor signaling pathway	Plxna2	IDA		Mouse	PMID:18327254
Biological Process	GO:0051642	centrosome localization	Plxna2	IMP	MGI:MGI:3793763	Mouse	PMID:18327254
Biological Process	GO:0021935	cerebellar granule cell precursor tangential migration	Plxna2	IMP	MGI:MGI:3793763	Mouse	PMID:18327254
Biological Process	GO:0021935	cerebellar granule cell precursor tangential migration	Plxna2	IMP	MGI:MGI:3793765	Mouse	PMID:18327254
Biological Process	GO:0001654	eye development	plxna2	IMP	ZFIN:ZDB-MRPHLNO-150427-2	Zfish	PMID:29091353
Biological Process	GO:0060174	limb bud formation	Plxna2	IEP		Mouse	MGI:MGI:4355631|PMID:19666519
Biological Process	GO:0021915	neural tube development	Plxna2	IEP		Mouse	MGI:MGI:4355631|PMID:19666519
Biological Process	GO:0003403	optic vesicle formation	plxna2	IMP	ZFIN:ZDB-MRPHLNO-150427-2	Zfish	PMID:24917502
Biological Process	GO:0003403	optic vesicle formation	plxna2	IGI	ZFIN:ZDB-MRPHLNO-140821-3,ZFIN:ZDB-MRPHLNO-150427-2	Zfish	PMID:24917502
Biological Process	GO:0060037	pharyngeal system development	Plxna2	IEP		Mouse	MGI:MGI:4355631|PMID:19666519
Biological Process	GO:0030334	regulation of cell migration	Plxna2	IMP		Mouse	MGI:MGI:5306550|PMID:20877282
Biological Process	GO:0071526	semaphorin-plexin signaling pathway	Plxna2	IPI	PR:O35464	Mouse	MGI:MGI:3793563|PMID:18327254
Biological Process	GO:0071526	semaphorin-plexin signaling pathway	Plxna2	IMP		Mouse	MGI:MGI:5306550|PMID:20877282
Biological Process	GO:0001756	somitogenesis	Plxna2	IEP		Mouse	MGI:MGI:4355631|PMID:19666519

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern