Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLSCR3
  • Mouse genes Plscr3
  • Rat genes Plscr3
  • Zfish genes plscr3a,plscr3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Plscr3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	PLSCR3	IMP		Human	PMID:18358005
Molecular Function	GO:0005509	calcium ion binding	PLSCR3	IMP		Human	PMID:29337693
Molecular Function	GO:0005509	calcium ion binding	PLSCR3	IMP		Human	PMID:31769662
Molecular Function	GO:0005509	calcium ion binding	Plscr3	IDA		Rat	PMID:29171872|RGD:30309908
Molecular Function	GO:0048306	calcium-dependent protein binding	PLSCR3	IPI	UniProtKB:O75340	Human	PMID:18256029
Molecular Function	GO:0032791	lead ion binding	PLSCR3	IMP		Human	PMID:31769662
Molecular Function	GO:0000287	magnesium ion binding	PLSCR3	IMP		Human	PMID:29337693
Molecular Function	GO:0045340	mercury ion binding	PLSCR3	IMP		Human	PMID:31769662
Molecular Function	GO:0017128	phospholipid scramblase activity	PLSCR3	IMP		Human	PMID:14573790
Molecular Function	GO:0017128	phospholipid scramblase activity	PLSCR3	IMP		Human	PMID:18358005
Molecular Function	GO:0017128	phospholipid scramblase activity	PLSCR3	IMP		Human	PMID:29337693
Molecular Function	GO:0017128	phospholipid scramblase activity	PLSCR3	IMP		Human	PMID:31769662
Molecular Function	GO:0017128	phospholipid scramblase activity	Plscr3	IDA		Rat	PMID:29171872|RGD:30309908
Molecular Function	GO:0005515	protein binding	PLSCR3	IPI	UniProtKB:Q05655	Human	PMID:12649167
Molecular Function	GO:0005515	protein binding	PLSCR3	IPI	UniProtKB:Q15645	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	PLSCR3	IPI	UniProtKB:O75340	Human	PMID:18256029
Molecular Function	GO:0005515	protein binding	PLSCR3	IPI	UniProtKB:O75716	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PLSCR3	IPI	UniProtKB:Q15645	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PLSCR3	IPI	UniProtKB:Q8NEC5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PLSCR3	IPI	UniProtKB:O14633	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLSCR3	IPI	UniProtKB:O60336	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLSCR3	IPI	UniProtKB:O75716	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLSCR3	IPI	UniProtKB:P27658	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLSCR3	IPI	UniProtKB:P41227	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLSCR3	IPI	UniProtKB:P49639	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLSCR3	IPI	UniProtKB:P49901	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLSCR3	IPI	UniProtKB:P78337	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLSCR3	IPI	UniProtKB:Q06455-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLSCR3	IPI	UniProtKB:Q0VD86	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLSCR3	IPI	UniProtKB:Q15645	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLSCR3	IPI	UniProtKB:Q15915	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLSCR3	IPI	UniProtKB:Q3LI64	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLSCR3	IPI	UniProtKB:Q3LI70	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLSCR3	IPI	UniProtKB:Q3LI76	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLSCR3	IPI	UniProtKB:Q3SYF9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLSCR3	IPI	UniProtKB:Q5BKX5-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLSCR3	IPI	UniProtKB:Q5SWW7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLSCR3	IPI	UniProtKB:Q5SY68	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLSCR3	IPI	UniProtKB:Q5T751	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLSCR3	IPI	UniProtKB:Q5TA78	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLSCR3	IPI	UniProtKB:Q5TCM9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLSCR3	IPI	UniProtKB:Q63HR2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLSCR3	IPI	UniProtKB:Q6P5X5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLSCR3	IPI	UniProtKB:Q8IUC1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLSCR3	IPI	UniProtKB:Q8NEC5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLSCR3	IPI	UniProtKB:Q96DL1-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLSCR3	IPI	UniProtKB:Q96KP6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLSCR3	IPI	UniProtKB:Q9BYR6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLSCR3	IPI	UniProtKB:Q9BYR7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLSCR3	IPI	UniProtKB:Q9NZC7-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLSCR3	IPI	UniProtKB:Q9NZN9	Human	PMID:32296183
Molecular Function	GO:0043621	protein self-association	PLSCR3	IDA		Human	PMID:29337693
Molecular Function	GO:0043621	protein self-association	PLSCR3	IDA		Human	PMID:31769662
Cellular Component	GO:0005829	cytosol	PLSCR3	IDA		Human	PMID:12649167
Cellular Component	GO:0005743	mitochondrial inner membrane	Plscr3	IDA		Rat	PMID:29171872|RGD:30309908
Cellular Component	GO:0005739	mitochondrion	PLSCR3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	PLSCR3	IDA		Human	PMID:12649167
Cellular Component	GO:0005739	mitochondrion	PLSCR3	IDA		Human	PMID:14573790
Cellular Component	GO:0005739	mitochondrion	PLSCR3	IDA		Human	PMID:18491232
Cellular Component	GO:0005739	mitochondrion	Plscr3	IDA		Mouse	MGI:MGI:6436981|PMID:21785166
Cellular Component	GO:0005739	mitochondrion	Plscr3	IDA		Rat	PMID:19428821|RGD:12904031
Cellular Component	GO:0005634	nucleus	Plscr3	IDA		Mouse	MGI:MGI:6436981|PMID:21785166
Cellular Component	GO:0005886	plasma membrane	PLSCR3	IDA		Human	PMID:19333378
Biological Process	GO:0006915	apoptotic process	PLSCR3	IMP		Human	PMID:12649167
Biological Process	GO:0006915	apoptotic process	Plscr3	IMP		Mouse	MGI:MGI:6436981|PMID:21785166
Biological Process	GO:0032049	cardiolipin biosynthetic process	PLSCR3	IMP		Human	PMID:16939411
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Plscr3	IEP		Mouse	MGI:MGI:3762685|PMID:17590392
Biological Process	GO:0042632	cholesterol homeostasis	Plscr3	IMP	MGI:MGI:3053448	Mouse	PMID:15328404
Biological Process	GO:0042593	glucose homeostasis	Plscr3	IMP	MGI:MGI:3053448	Mouse	PMID:15328404
Biological Process	GO:0042981	regulation of apoptotic process	PLSCR3	IMP		Human	PMID:14573790
Biological Process	GO:0042981	regulation of apoptotic process	PLSCR3	IMP		Human	PMID:18358005
Biological Process	GO:0042981	regulation of apoptotic process	PLSCR3	IMP		Human	PMID:18491232
Biological Process	GO:0090199	regulation of release of cytochrome c from mitochondria	PLSCR3	IMP		Human	PMID:14573790
Biological Process	GO:0090199	regulation of release of cytochrome c from mitochondria	PLSCR3	IMP		Human	PMID:18358005

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern