Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Plpp1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes PLPP1
- Mouse genes Plpp1
- Rat genes Plpp1
- Zfish genes plpp1a
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Plpp1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0106235	ceramide-1-phosphate phosphatase activity	PLPP1	IDA		Human	PMID:9705349
Molecular Function	GO:0106235	ceramide-1-phosphate phosphatase activity	Plpp1	IDA		Mouse	MGI:MGI:6383560\|PMID:10359651
Molecular Function	GO:0106235	ceramide-1-phosphate phosphatase activity	Plpp1	IDA		Rat	PMID:10359651\|RGD:15090857
Molecular Function	GO:0000810	diacylglycerol diphosphate phosphatase activity	Plpp1	IDA		Mouse	MGI:MGI:6383560\|PMID:10359651
Molecular Function	GO:0000810	diacylglycerol diphosphate phosphatase activity	Plpp1	IMP		Mouse	MGI:MGI:3849130\|PMID:19215222
Molecular Function	GO:0000810	diacylglycerol diphosphate phosphatase activity	Plpp1	IDA		Rat	PMID:10359651\|RGD:15090857
Molecular Function	GO:0000810	diacylglycerol diphosphate phosphatase activity	Plpp1	IDA		Rat	PMID:8663293\|RGD:15090855
Molecular Function	GO:0042577	lipid phosphatase activity	PLPP1	IDA		Human	PMID:15461590
Molecular Function	GO:0042577	lipid phosphatase activity	PLPP1	IDA		Human	PMID:16464866
Molecular Function	GO:0042577	lipid phosphatase activity	Plpp1	IDA		Mouse	MGI:MGI:6383318\|PMID:15461590
Molecular Function	GO:0008195	phosphatidate phosphatase activity	PLPP1	IDA		Human	PMID:9305923
Molecular Function	GO:0008195	phosphatidate phosphatase activity	PLPP1	IDA		Human	PMID:9468526
Molecular Function	GO:0008195	phosphatidate phosphatase activity	PLPP1	IDA		Human	PMID:9705349
Molecular Function	GO:0008195	phosphatidate phosphatase activity	Plpp1	IMP		Mouse	MGI:MGI:3849130\|PMID:19215222
Molecular Function	GO:0008195	phosphatidate phosphatase activity	Plpp1	IDA		Mouse	MGI:MGI:6383560\|PMID:10359651
Molecular Function	GO:0008195	phosphatidate phosphatase activity	Plpp1	IDA		Mouse	PMID:8702556
Molecular Function	GO:0008195	phosphatidate phosphatase activity	Plpp1	IDA		Rat	PMID:10359651\|RGD:15090857
Molecular Function	GO:0008195	phosphatidate phosphatase activity	Plpp1	IDA		Rat	PMID:8663293\|RGD:15090855
Molecular Function	GO:0005515	protein binding	PLPP1	IPI	UniProtKB:O15529	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLPP1	IPI	UniProtKB:Q8WWF3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLPP1	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PLPP1	IPI	UniProtKB:P17612	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PLPP1	IPI	UniProtKB:P29466-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PLPP1	IPI	UniProtKB:P48730-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PLPP1	IPI	UniProtKB:P49768-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PLPP1	IPI	UniProtKB:Q15583	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	PLPP1	IPI	UniProtKB:Q9UQM7	Human	PMID:32814053
Molecular Function	GO:0042392	sphingosine-1-phosphate phosphatase activity	PLPP1	IDA		Human	PMID:9705349
Molecular Function	GO:0042392	sphingosine-1-phosphate phosphatase activity	Plpp1	IDA		Mouse	MGI:MGI:6383560\|PMID:10359651
Molecular Function	GO:0042392	sphingosine-1-phosphate phosphatase activity	Plpp1	IDA		Rat	PMID:10359651\|RGD:15090857
Molecular Function	GO:0042392	sphingosine-1-phosphate phosphatase activity	Plpp1	IDA		Rat	PMID:8663293\|RGD:15090855
Cellular Component	GO:0016324	apical plasma membrane	PLPP1	IDA		Human	PMID:14527693
Cellular Component	GO:0005901	caveola	Plpp1	IDA		Mouse	MGI:MGI:6383562\|PMID:11535125
Cellular Component	GO:0070062	extracellular exosome	PLPP1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	PLPP1	HDA		Human	PMID:23533145
Cellular Component	GO:0016020	membrane	PLPP1	IDA		Human	PMID:9305923
Cellular Component	GO:0016020	membrane	PLPP1	IDA		Human	PMID:9468526
Cellular Component	GO:0045121	membrane raft	PLPP1	IDA		Human	PMID:17005594
Cellular Component	GO:0005886	plasma membrane	PLPP1	IDA		Human	PMID:9705349
Cellular Component	GO:0005886	plasma membrane	Plpp1	IDA		Mouse	MGI:MGI:3849130\|PMID:19215222
Cellular Component	GO:0005886	plasma membrane	Plpp1	IDA		Rat	PMID:10359651\|RGD:15090857
Cellular Component	GO:0005886	plasma membrane	Plpp1	IDA		Rat	PMID:8663293\|RGD:15090855
Biological Process	GO:0006672	ceramide metabolic process	PLPP1	IDA		Human	PMID:9305923
Biological Process	GO:0006672	ceramide metabolic process	PLPP1	IDA		Human	PMID:9705349
Biological Process	GO:0006672	ceramide metabolic process	Plpp1	IDA		Mouse	MGI:MGI:6383560\|PMID:10359651
Biological Process	GO:0006672	ceramide metabolic process	Plpp1	IDA		Rat	PMID:10359651\|RGD:15090857
Biological Process	GO:0006672	ceramide metabolic process	Plpp1	IDA		Rat	PMID:8663293\|RGD:15090855
Biological Process	GO:0046839	phospholipid dephosphorylation	PLPP1	IDA		Human	PMID:15461590
Biological Process	GO:0046839	phospholipid dephosphorylation	PLPP1	IDA		Human	PMID:16464866
Biological Process	GO:0046839	phospholipid dephosphorylation	PLPP1	IDA		Human	PMID:9305923
Biological Process	GO:0046839	phospholipid dephosphorylation	PLPP1	IDA		Human	PMID:9705349
Biological Process	GO:0046839	phospholipid dephosphorylation	Plpp1	IDA		Mouse	MGI:MGI:6383318\|PMID:15461590
Biological Process	GO:0046839	phospholipid dephosphorylation	Plpp1	IMP		Mouse	MGI:MGI:3849130\|PMID:19215222
Biological Process	GO:0046839	phospholipid dephosphorylation	Plpp1	IDA		Mouse	MGI:MGI:6383560\|PMID:10359651
Biological Process	GO:0046839	phospholipid dephosphorylation	Plpp1	IDA		Rat	PMID:10359651\|RGD:15090857
Biological Process	GO:0046839	phospholipid dephosphorylation	Plpp1	IDA		Rat	PMID:8663293\|RGD:15090855
Biological Process	GO:0006644	phospholipid metabolic process	PLPP1	IDA		Human	PMID:15461590
Biological Process	GO:0006644	phospholipid metabolic process	PLPP1	IDA		Human	PMID:9305923
Biological Process	GO:0006644	phospholipid metabolic process	PLPP1	IDA		Human	PMID:9705349
Biological Process	GO:0006644	phospholipid metabolic process	Plpp1	IDA		Mouse	MGI:MGI:6383560\|PMID:10359651
Biological Process	GO:0006644	phospholipid metabolic process	Plpp1	IDA		Mouse	MGI:MGI:6383318\|PMID:15461590
Biological Process	GO:0006644	phospholipid metabolic process	Plpp1	IDA		Rat	PMID:10359651\|RGD:15090857
Biological Process	GO:0007165	signal transduction	PLPP1	IMP		Human	PMID:15461590
Biological Process	GO:0007165	signal transduction	Plpp1	IMP		Mouse	MGI:MGI:6383560\|PMID:10359651
Biological Process	GO:0007165	signal transduction	Plpp1	IMP		Mouse	MGI:MGI:6383318\|PMID:15461590
Biological Process	GO:0006670	sphingosine metabolic process	PLPP1	IDA		Human	PMID:9705349
Biological Process	GO:0006670	sphingosine metabolic process	Plpp1	IDA		Mouse	MGI:MGI:6383560\|PMID:10359651
Biological Process	GO:0006670	sphingosine metabolic process	Plpp1	IDA		Rat	PMID:10359651\|RGD:15090857
Biological Process	GO:0006670	sphingosine metabolic process	Plpp1	IDA		Rat	PMID:8663293\|RGD:15090855

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/30/2025 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.