Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLOD1
  • Mouse genes Plod1
  • Rat genes Plod1
  • Zfish genes plod1a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Plod1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008198	ferrous iron binding	Plod1	IMP		Rat	PMID:11714250|RGD:1599090
Molecular Function	GO:0031418	L-ascorbic acid binding	Plod1	IMP		Rat	PMID:11714250|RGD:1599090
Molecular Function	GO:0042277	peptide binding	Plod1	IDA		Rat	PMID:11714250|RGD:1599090
Molecular Function	GO:0042277	peptide binding	Plod1	IMP		Rat	PMID:11714250|RGD:1599090
Molecular Function	GO:0008475	procollagen-lysine 5-dioxygenase activity	PLOD1	IDA		Human	PMID:10934207
Molecular Function	GO:0008475	procollagen-lysine 5-dioxygenase activity	PLOD1	IMP		Human	PMID:8621606
Molecular Function	GO:0008475	procollagen-lysine 5-dioxygenase activity	PLOD1	IDA		Human	PMID:9724729
Molecular Function	GO:0008475	procollagen-lysine 5-dioxygenase activity	Plod1	IDA		Rat	PMID:11714250|RGD:1599090
Molecular Function	GO:0008475	procollagen-lysine 5-dioxygenase activity	Plod1	IMP		Rat	PMID:11714250|RGD:1599090
Molecular Function	GO:0005515	protein binding	PLOD1	IPI	UniProtKB:P55795	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	PLOD1	IPI	UniProtKB:P55795	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	Plod1	IPI	UniProtKB:Q8K2B0	Mouse	MGI:MGI:5779580|PMID:27119146
Cellular Component	GO:1902494	catalytic complex	Plod1	IMP		Mouse	MGI:MGI:5779580|PMID:27119146
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Plod1	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0070062	extracellular exosome	PLOD1	HDA		Human	PMID:19056867
Biological Process	GO:0032870	cellular response to hormone stimulus	Plod1	IEP		Rat	PMID:15817667|RGD:2314536
Biological Process	GO:0008544	epidermis development	PLOD1	IMP		Human	PMID:8449506
Biological Process	GO:0033333	fin development	plod1a	IMP	ZFIN:ZDB-MRPHLNO-110630-4	Zfish	PMID:21420398
Biological Process	GO:0033334	fin morphogenesis	plod1a	IMP	ZFIN:ZDB-MRPHLNO-110630-4	Zfish	PMID:21420398
Biological Process	GO:0017185	peptidyl-lysine hydroxylation	PLOD1	IDA		Human	PMID:10934207
Biological Process	GO:0017185	peptidyl-lysine hydroxylation	PLOD1	IDA		Human	PMID:8621606
Biological Process	GO:0017185	peptidyl-lysine hydroxylation	PLOD1	IDA		Human	PMID:9724729
Biological Process	GO:0017185	peptidyl-lysine hydroxylation	Plod1	IDA		Rat	PMID:11714250|RGD:1599090
Biological Process	GO:0017185	peptidyl-lysine hydroxylation	Plod1	IDA		Rat	PMID:7578263|RGD:734487
Biological Process	GO:0001666	response to hypoxia	PLOD1	IEP		Human	PMID:15174142
Biological Process	GO:0001666	response to hypoxia	Plod1	IEP		Rat	PMID:14622280|RGD:1303932

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern