Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLEKHA5
  • Mouse genes Plekha5
  • Rat genes Plekha5
  • Zfish genes plekha5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Plekha5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	Plekha5	IDA		Mouse	PMID:22037487
Molecular Function	GO:0032266	phosphatidylinositol-3-phosphate binding	Plekha5	IDA		Mouse	PMID:22037487
Molecular Function	GO:0070273	phosphatidylinositol-4-phosphate binding	Plekha5	IDA		Mouse	PMID:22037487
Molecular Function	GO:0010314	phosphatidylinositol-5-phosphate binding	Plekha5	IDA		Mouse	PMID:22037487
Molecular Function	GO:0005515	protein binding	PLEKHA5	IPI	UniProtKB:P54253	Human	PMID:16713569
Molecular Function	GO:0005515	protein binding	PLEKHA5	IPI	UniProtKB:P54259	Human	PMID:16713569
Molecular Function	GO:0005515	protein binding	PLEKHA5	IPI	UniProtKB:Q9NWB1	Human	PMID:16713569
Molecular Function	GO:0005515	protein binding	PLEKHA5	IPI	UniProtKB:Q5EBL8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	PLEKHA5	IPI	UniProtKB:Q5EBL8	Human	PMID:32296183
Cellular Component	GO:0005829	cytosol	PLEKHA5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Plekha5	IDA		Mouse	PMID:22037487
Cellular Component	GO:0098978	glutamatergic synapse	Plekha5	IDA		Mouse	PMID:28935861
Cellular Component	GO:0098978	glutamatergic synapse	Plekha5	EXP		Mouse	PMID:28935861
Cellular Component	GO:0016020	membrane	PLEKHA5	HDA		Human	PMID:19946888
Cellular Component	GO:0005654	nucleoplasm	PLEKHA5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0014069	postsynaptic density	Plekha5	IDA		Mouse	PMID:28935861
Cellular Component	GO:0014069	postsynaptic density	Plekha5	EXP		Mouse	PMID:28935861
Biological Process	GO:0061458	reproductive system development	Plekha5	IGI	MGI:MGI:88064	Mouse	PMID:19574395

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern