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Plekha5
Gene Detail
Symbol

Name
ID
Plekha5
pleckstrin homology domain containing, family A member 5
MGI:1923802
Synonyms
2810431N21Rik, AMH-Cre, Ayu21-9, Gt(Ayu21)9Imeg, PEPP2, Tg(AMH-cre)1Flor
Feature Type
protein coding gene
Genetic Map
Chromosome 6
70.34 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr6:140424099-140594906 bp, + strand
From Ensembl annotation of GRCm38

  170808 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:10377  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Plekha5

Human
homologs
Human Homolog PLEKHA5, pleckstrin homology domain containing, family A member 5
NCBI Gene ID 54477
neXtProt AC  NX_Q9HAU0
Human Synonyms  PEPP2, PEPP-2
Human Chr (Location)  12p12; chr12:19129692-19376400 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(43) : Gene trapped(41) Targeted(1) Transgenic(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Plekha5 interacts with 208 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (7 annotations)
Process reproductive system development
Component cytosol, membrane
Function phosphatidylinositol-3,5-bisphosphate binding, phosphatidylinositol-3-phosphate binding, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (165)    Tissues (47)    Images (40)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 165
cDNA source data(110)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(110) cDNA(110)
Microarray probesets(6)
Other database
links
Ensembl Gene ModelENSMUSG00000030231 (Evidence)
Entrez Gene109135 (Evidence)
UniGene247670
DFCITC1670619, TC1602947, TC1601170, TC1590012, TC1578983
DoTSDT.94199280, DT.94153610, DT.55265874, DT.94153608, DT.527093, DT.101235710, DT.97371331, DT.489739, DT.97371334, DT.101738012
NIA Mouse Gene IndexU007525
Consensus CDS ProjectCCDS39688.1
International Mouse Knockout Project StatusPlekha5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000030231 Ensembl Gene Model | MGI Sequence Detail 170808 C57BL/6J ±  kb
transcript ENSMUST00000087622 Ensembl | MGI Sequence Detail 5133 Not Applicable 
polypeptide ENSMUSP00000084904 Ensembl | MGI Sequence Detail 1269 Not Applicable 

For the selected sequences
All sequences(133) RefSeq(85) UniProt(10)
Polymorphisms
SNPs within 2kb(1312 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001849 Pleckstrin homology domain
InterPro IPR011993 Pleckstrin homology-like domain
InterPro IPR001202 WW domain
References
(Earliest) J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
(Latest) J:213587 Rebourcet D, et al., Sertoli cells control peritubular myoid cell fate and support adult Leydig cell development in the prepubertal testis. Development. 2014 May;141(10):2139-49
All references(88)
Other
accession IDs
MGI:1889819, MGI:2450303, MGI:3527252, MGI:3629683

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory