Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLD3
  • Mouse genes Pld3
  • Rat genes Pld3
  • Zfish genes pld3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pld3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	PLD3	IPI	UniProtKB:P19838	Human	PMID:20195357
Molecular Function	GO:0005515	protein binding	PLD3	IPI	UniProtKB:P05067	Human	PMID:24336208
Molecular Function	GO:0005515	protein binding	PLD3	IPI	UniProtKB:P35372-10	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLD3	IPI	UniProtKB:Q8TBE1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PLD3	IPI	UniProtKB:Q9NRQ5	Human	PMID:32296183
Molecular Function	GO:0045145	single-stranded DNA 5'-3' DNA exonuclease activity	PLD3	IDA		Human	PMID:30312375
Molecular Function	GO:0045145	single-stranded DNA 5'-3' DNA exonuclease activity	Pld3	IDA		Mouse	MGI:MGI:6377989|PMID:30111894
Cellular Component	GO:0031901	early endosome membrane	PLD3	IDA		Human	PMID:29386126
Cellular Component	GO:0005789	endoplasmic reticulum membrane	PLD3	IDA		Human	PMID:15794758
Cellular Component	GO:0005789	endoplasmic reticulum membrane	PLD3	IDA		Human	PMID:22428023
Cellular Component	GO:0070062	extracellular exosome	PLD3	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	PLD3	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	PLD3	HDA		Human	PMID:23533145
Cellular Component	GO:0000139	Golgi membrane	PLD3	IDA		Human	PMID:29368044
Cellular Component	GO:0031902	late endosome membrane	PLD3	IDA		Human	PMID:29386126
Cellular Component	GO:0031902	late endosome membrane	Pld3	IDA		Mouse	MGI:MGI:6115966|PMID:28128235
Cellular Component	GO:0043202	lysosomal lumen	PLD3	IDA		Human	PMID:30312375
Cellular Component	GO:0005765	lysosomal membrane	Pld3	IDA		Mouse	MGI:MGI:6115966|PMID:28128235
Biological Process	GO:0014902	myotube differentiation	PLD3	IDA		Human	PMID:22428023
Biological Process	GO:1900015	regulation of cytokine production involved in inflammatory response	Pld3	IMP		Mouse	MGI:MGI:5308480|PMID:22102906

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern