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Pld3
Gene Detail
 Symbol
Name
ID
Pld3
phospholipase D family, member 3
MGI:1333782
Synonyms Sam-9
Feature Type protein coding gene
Genetic Map
Chromosome 7
15.92 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:27532000-27553218 bp, - strand
From VEGA annotation of GRCm38

  21219 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7893  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: phospholipase D, chordopox type
Gene Tree: Pld3

Human
homologs
Human Homolog PLD3, phospholipase D family, member 3
NCBI Gene ID 23646
neXtProt AC  NX_Q8IV08
Human Synonyms  AD19, HUK4, HU-K4
Human Chr (Location)  19q13.2; chr19:40348395-40378485 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human PLD3
Mutations,
alleles, and
phenotypes
All mutations/alleles(99) : Gene trapped(97) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Pld3 interacts with 84 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process lipid catabolic process, lipid metabolic process, ...
Component endoplasmic reticulum, extracellular vesicular exosome, ...
Function catalytic activity, hydrolase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (130)    Tissues (107)    Images (17)
Theiler Stages: 22, 26, 28
Assay TypeResults
RNA in situ 95
Northern blot 35
cDNA source data(173)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(177) Genomic(1) cDNA(174) Primer pair(1) Other(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000031815 (Evidence)
Ensembl Gene ModelENSMUSG00000003363 (Evidence)
Entrez Gene18807 (Evidence)
UniGene6483
DFCITC1572347
DoTSDT.101130985, DT.494005
NIA Mouse Gene IndexU028303
EC3.1.4.4
Consensus CDS ProjectCCDS21025.1
International Mouse Knockout Project StatusPld3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031815 VEGA Gene Model | MGI Sequence Detail 21219 C57BL/6J ±  kb
transcript OTTMUST00000078885 VEGA | MGI Sequence Detail 2282 Not Applicable 
polypeptide OTTMUSP00000042001 VEGA | MGI Sequence Detail 488 Not Applicable 

For the selected sequences
All sequences(64) RefSeq(12) UniProt(4)
Polymorphisms SNPs within 2kb(74 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001736 Phospholipase D/Transphosphatidylase
Protein Ontology PR:000012845 phospholipase D3
References (Earliest) J:51052 Roy IL, et al., Quantitative trait loci implicated in corpus callosum midsagittal area in mice. Brain Res. 1998 Nov 16;811(1-2):173-6
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(38)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory