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Pld3
Gene Detail
Symbol

Name
ID
Pld3
phospholipase D family, member 3
MGI:1333782
Synonyms
Sam-9
Feature Type
protein coding gene
Genetic Map
Chromosome 7
15.92 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:27532000-27553218 bp, - strand
From VEGA annotation of GRCm38

  21219 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:7893  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: PLD3
Protein SuperFamily: phospholipase D, chordopox type
Gene Tree: Pld3

Human
homologs
PLD3, phospholipase D family, member 3
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 23646
neXtProt AC: NX_Q8IV08

Human Synonyms: AD19, HUK4, HU-K4

Human Chr (Location): 19q13.2; chr19:40348425-40378490 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human PLD3

Mutations,
alleles, and
phenotypes
All mutations/alleles(99) : Gene trapped(97) Targeted(2)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Pld3 interacts with 84 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (10 annotations)
Process lipid catabolic process, lipid metabolic process
Component endoplasmic reticulum, extracellular exosome, ...
Function catalytic activity, hydrolase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (130)    Tissues (107)    Images (17)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 95
Northern blot 35
cDNA source data(173)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: Xenbase pld3    NEW 
Molecular
reagents
All nucleic(177) Genomic(1) cDNA(174) Primer pair(1) Other(1)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000031815 (Evidence)
Ensembl Gene Model ENSMUSG00000003363 (Evidence)
Entrez Gene 18807 (Evidence)
UniGene 6483
DFCI TC1572347
DoTS DT.494005, DT.101130985
NIA Mouse Gene Index U028303
EC 3.1.4.4
Consensus CDS Project CCDS21025.1
International Mouse Phenotyping Consortium Status Pld3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031815 VEGA Gene Model | MGI Sequence Detail 21219 C57BL/6J ±  kb
transcript OTTMUST00000078885 VEGA | MGI Sequence Detail 2282 Not Applicable 
polypeptide OTTMUSP00000042001 VEGA | MGI Sequence Detail 488 Not Applicable 

For the selected sequences
All sequences(69) RefSeq(16) UniProt(4)
Polymorphisms
SNPs within 2kb(74 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001736 Phospholipase D/Transphosphatidylase
Protein Ontology PR:000012845 phospholipase D3
References
(Earliest) J:51052 Roy IL, et al., Quantitative trait loci implicated in corpus callosum midsagittal area in mice. Brain Res. 1998 Nov 16;811(1-2):173-6
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(37)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory