Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLCZ1
  • Mouse genes Plcz1
  • Rat genes Plcz1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Plcz1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004435	phosphatidylinositol phospholipase C activity	PLCZ1	IDA		Human	PMID:28270562
Molecular Function	GO:0004435	phosphatidylinositol phospholipase C activity	Plcz1	IDA		Mouse	MGI:MGI:3037365|PMID:14701816
Molecular Function	GO:0032266	phosphatidylinositol-3-phosphate binding	PLCZ1	IMP		Human	PMID:28270562
Molecular Function	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	PLCZ1	IDA		Human	PMID:28270562
Molecular Function	GO:0010314	phosphatidylinositol-5-phosphate binding	PLCZ1	IMP		Human	PMID:28270562
Molecular Function	GO:0004629	phospholipase C activity	Plcz1	IDA		Mouse	PMID:12117804
Cellular Component	GO:0005737	cytoplasm	Plcz1	IDA		Rat	PMID:18322275|RGD:13507301
Cellular Component	GO:0005730	nucleolus	Plcz1	IDA		Mouse	MGI:MGI:6120337|PMID:18322275
Cellular Component	GO:0005654	nucleoplasm	Plcz1	IDA		Mouse	MGI:MGI:6120337|PMID:18322275
Cellular Component	GO:0005634	nucleus	PLCZ1	IDA		Human	PMID:18322275
Cellular Component	GO:0045120	pronucleus	Plcz1	IDA		Mouse	MGI:MGI:6120337|PMID:18322275
Cellular Component	GO:0061827	sperm head	PLCZ1	IMP		Human	PMID:26721930
Biological Process	GO:0006816	calcium ion transport	Plcz1	IDA		Mouse	PMID:12117804
Biological Process	GO:0007343	egg activation	PLCZ1	IMP		Human	PMID:26721930
Biological Process	GO:0007343	egg activation	Plcz1	IDA		Mouse	PMID:12117804
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	PLCZ1	IMP		Human	PMID:26721930
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	PLCZ1	IMP		Human	PMID:28270562
Biological Process	GO:0060470	positive regulation of cytosolic calcium ion concentration involved in egg activation	PLCZ1	IDA		Human	PMID:18322275
Biological Process	GO:0060470	positive regulation of cytosolic calcium ion concentration involved in egg activation	PLCZ1	IDA		Human	PMID:26116451
Biological Process	GO:0060470	positive regulation of cytosolic calcium ion concentration involved in egg activation	Plcz1	IDA		Mouse	MGI:MGI:6120337|PMID:18322275
Biological Process	GO:0060470	positive regulation of cytosolic calcium ion concentration involved in egg activation	Plcz1	IDA		Rat	PMID:18322275|RGD:13507301

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern