MGI 5.13 - Gene Ontology Browser

Gene Ontology Browser
Term Detail

GO term:	phosphatidylinositol phospholipase C activity
Synonym:	1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase activity
Synonym:	1-phosphatidyl-D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase activity
Synonym:	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase activity
Synonym:	monophosphatidylinositol phosphodiesterase activity
Synonym:	phosphatidylinositol-4,5-bisphosphate hydrolysis
Synonym:	phosphoinositidase C activity
Synonym:	phosphoinositide phospholipase C activity
Synonym:	PI-PLC activity
Synonym:	triphosphoinositide phosphodiesterase activity
GO id:	GO:0004435
Definition:	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1,2-diacylglycerol + 1D-myo-inositol 1,4,5-trisphosphate + H(+).
Number of paths to term:	2

denotes an 'is-a' relationship
denotes a 'part-of' relationship
denotes a 'regulates' relationship
denotes a 'positively-regulates' relationship
denotes a 'negatively-regulates' relationship

Gene_Ontology

molecular_function

catalytic activity

hydrolase activity

hydrolase activity, acting on ester bonds

lipase activity

phospholipase activity

phospholipase C activity

calcium-dependent phospholipase C activity

inositol phosphosphingolipid phospholipase activity +

phosphatidylcholine phospholipase C activity

phosphatidylglycerol phospholipase C activity

phosphatidylinositol phospholipase C activity [GO:0004435] (19 genes, 20 annotations)