Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLAUR
  • Mouse genes Plaur
  • Rat genes Plaur
  • Zfish genes ly6m4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Plaur

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019899	enzyme binding	PLAUR	IPI	UniProtKB:P08246	Human	PMID:14688365
Molecular Function	GO:0019899	enzyme binding	PLAUR	IPI	UniProtKB:P0C0G7	Human	PMID:15922359
Molecular Function	GO:0005515	protein binding	PLAUR	IPI	UniProtKB:P01042	Human	PMID:11290596
Molecular Function	GO:0005515	protein binding	PLAUR	IPI	UniProtKB:Q92673	Human	PMID:14764453
Molecular Function	GO:0005515	protein binding	PLAUR	IPI	UniProtKB:P0C0G7	Human	PMID:15922359
Molecular Function	GO:0005515	protein binding	PLAUR	IPI	UniProtKB:O60687	Human	PMID:18718938
Molecular Function	GO:0005515	protein binding	PLAUR	IPI	UniProtKB:P03950	Human	PMID:24457100
Molecular Function	GO:0005515	protein binding	Plaur	IPI	UniProtKB:Q8R054	Mouse	MGI:MGI:4412425|PMID:19667118
Molecular Function	GO:0019904	protein domain specific binding	PLAUR	IPI	UniProtKB:P08169	Human	PMID:12665524
Molecular Function	GO:0005102	signaling receptor binding	PLAUR	IPI	UniProtKB:P08169	Human	PMID:12665524
Cellular Component	GO:0009986	cell surface	PLAUR	IDA		Human	PMID:15922359
Cellular Component	GO:0005925	focal adhesion	PLAUR	HDA		Human	PMID:21423176
Cellular Component	GO:0005886	plasma membrane	PLAUR	IDA		Human	PMID:12665524
Cellular Component	GO:0005886	plasma membrane	Plaur	IDA		Mouse	PMID:19897580
Cellular Component	GO:0098637	protein complex involved in cell-matrix adhesion	PLAUR	IPI		Human	PMID:24465541
Cellular Component	GO:1905370	serine-type endopeptidase complex	PLAUR	IPI		Human	PMID:22285761
Cellular Component	GO:1905370	serine-type endopeptidase complex	Plaur	IPI		Mouse	MGI:MGI:4838953|PMID:20133942
Biological Process	GO:0060742	epithelial cell differentiation involved in prostate gland development	Plaur	IMP		Rat	PMID:11798065|RGD:729659
Biological Process	GO:0048762	mesenchymal cell differentiation	Plaur	IMP		Rat	PMID:11798065|RGD:729659
Biological Process	GO:0043066	negative regulation of apoptotic process	PLAUR	IMP		Human	PMID:22984561
Biological Process	GO:0043066	negative regulation of apoptotic process	Plaur	IMP		Rat	PMID:11798065|RGD:729659
Biological Process	GO:2001268	negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	PLAUR	IMP		Human	PMID:22984561
Biological Process	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	PLAUR	IMP		Human	PMID:22984561
Biological Process	GO:0043388	positive regulation of DNA binding	PLAUR	IDA		Human	PMID:22984561
Biological Process	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway	PLAUR	IMP		Human	PMID:22984561
Biological Process	GO:0034112	positive regulation of homotypic cell-cell adhesion	PLAUR	IMP		Human	PMID:21679692
Biological Process	GO:0001934	positive regulation of protein phosphorylation	PLAUR	IMP		Human	PMID:22984561
Biological Process	GO:0090200	positive regulation of release of cytochrome c from mitochondria	PLAUR	IMP		Human	PMID:22984561
Biological Process	GO:0030155	regulation of cell adhesion	PLAUR	IDA		Human	PMID:10722842
Biological Process	GO:0043403	skeletal muscle tissue regeneration	Plaur	IEP		Rat	PMID:12919869|RGD:1581928
Biological Process	GO:0007283	spermatogenesis	Plaur	IEP		Rat	PMID:17712486|RGD:6484143

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern