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Gene Ontology Browser
Term Detail
GO term:mesenchymal cell differentiation
GO id:GO:0048762
Definition:The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types.
Number of paths to term: 11

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-abiological_process
                is-acellular process
                        is-asingle-organism cellular process
                                is-acellular developmental process
                                        is-acell differentiation
                                                is-astem cell differentiation
                                                        is-acardioblast differentiation +
                                                        is-ahematopoietic stem cell differentiation +
                                                        is-ahepatoblast differentiation
                                                        is-alimb basal epidermal cell differentiation +
                                                        is-amesenchymal cell differentiation [GO:0048762] (149 genes, 218 annotations)
                                                                is-aamniotic stem cell differentiation +
                                                                is-aangioblast cell differentiation
                                                                part-ofmesenchymal cell development +
                                                                is-amesenchymal cell differentiation involved in bone development
                                                                is-amesenchymal cell differentiation involved in lung development
                                                                is-amesenchymal cell differentiation involved in mammary gland development
                                                                is-amesenchymal cell differentiation involved in renal system development +
                                                                is-amesenchymal cell differentiation involved in salivary gland development
                                                                part-ofmesenchymal cell fate commitment
                                                                is-aneural crest cell differentiation +
                                                        is-amesenchymal stem cell differentiation +
                                                        negatively-regulatesnegative regulation of stem cell differentiation +
                                                        is-aneuroblast differentiation +
                                                        positively-regulatespositive regulation of stem cell differentiation +
                                                        regulatesregulation of stem cell differentiation +
                                                        is-arespiratory basal cell differentiation
                                                        part-ofstem cell development +
                                                        part-ofstem cell fate commitment +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-aanatomical structure development
                                is-aorgan development
                                        part-ofmesenchyme development
                                                is-aendocardial cushion development +
                                                is-agonadal mesoderm development
                                                is-akidney mesenchyme development +
                                                is-alateral mesoderm development +
                                                is-alung-associated mesenchyme development +
                                                part-ofmesenchymal cell differentiation [GO:0048762] (149 genes, 218 annotations)
                                                        is-aamniotic stem cell differentiation +
                                                        is-aangioblast cell differentiation
                                                        part-ofmesenchymal cell development +
                                                        is-amesenchymal cell differentiation involved in bone development
                                                        is-amesenchymal cell differentiation involved in lung development
                                                        is-amesenchymal cell differentiation involved in mammary gland development
                                                        is-amesenchymal cell differentiation involved in renal system development +
                                                        is-amesenchymal cell differentiation involved in salivary gland development
                                                        part-ofmesenchymal cell fate commitment
                                                        is-aneural crest cell differentiation +
                                                part-ofmesenchyme morphogenesis +
                                                is-ametanephric cortex development
                                                is-aparaxial mesoderm development +
                                                is-aproepicardium development
                                                is-asclerotome development +
                                                is-aseptum transversum development +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-aanatomical structure development
                                is-asystem development
                                        part-oforgan development
                                                part-ofmesenchyme development
                                                        is-aendocardial cushion development +
                                                        is-agonadal mesoderm development
                                                        is-akidney mesenchyme development +
                                                        is-alateral mesoderm development +
                                                        is-alung-associated mesenchyme development +
                                                        part-ofmesenchymal cell differentiation [GO:0048762] (149 genes, 218 annotations)
                                                                is-aamniotic stem cell differentiation +
                                                                is-aangioblast cell differentiation
                                                                part-ofmesenchymal cell development +
                                                                is-amesenchymal cell differentiation involved in bone development
                                                                is-amesenchymal cell differentiation involved in lung development
                                                                is-amesenchymal cell differentiation involved in mammary gland development
                                                                is-amesenchymal cell differentiation involved in renal system development +
                                                                is-amesenchymal cell differentiation involved in salivary gland development
                                                                part-ofmesenchymal cell fate commitment
                                                                is-aneural crest cell differentiation +
                                                        part-ofmesenchyme morphogenesis +
                                                        is-ametanephric cortex development
                                                        is-aparaxial mesoderm development +
                                                        is-aproepicardium development
                                                        is-asclerotome development +
                                                        is-aseptum transversum development +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-aanatomical structure development
                                is-atissue development
                                        is-amesenchyme development
                                                is-aendocardial cushion development +
                                                is-agonadal mesoderm development
                                                is-akidney mesenchyme development +
                                                is-alateral mesoderm development +
                                                is-alung-associated mesenchyme development +
                                                part-ofmesenchymal cell differentiation [GO:0048762] (149 genes, 218 annotations)
                                                        is-aamniotic stem cell differentiation +
                                                        is-aangioblast cell differentiation
                                                        part-ofmesenchymal cell development +
                                                        is-amesenchymal cell differentiation involved in bone development
                                                        is-amesenchymal cell differentiation involved in lung development
                                                        is-amesenchymal cell differentiation involved in mammary gland development
                                                        is-amesenchymal cell differentiation involved in renal system development +
                                                        is-amesenchymal cell differentiation involved in salivary gland development
                                                        part-ofmesenchymal cell fate commitment
                                                        is-aneural crest cell differentiation +
                                                part-ofmesenchyme morphogenesis +
                                                is-ametanephric cortex development
                                                is-aparaxial mesoderm development +
                                                is-aproepicardium development
                                                is-asclerotome development +
                                                is-aseptum transversum development +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-asingle-organism developmental process
                                is-acellular developmental process
                                        is-acell differentiation
                                                is-astem cell differentiation
                                                        is-acardioblast differentiation +
                                                        is-ahematopoietic stem cell differentiation +
                                                        is-ahepatoblast differentiation
                                                        is-alimb basal epidermal cell differentiation +
                                                        is-amesenchymal cell differentiation [GO:0048762] (149 genes, 218 annotations)
                                                                is-aamniotic stem cell differentiation +
                                                                is-aangioblast cell differentiation
                                                                part-ofmesenchymal cell development +
                                                                is-amesenchymal cell differentiation involved in bone development
                                                                is-amesenchymal cell differentiation involved in lung development
                                                                is-amesenchymal cell differentiation involved in mammary gland development
                                                                is-amesenchymal cell differentiation involved in renal system development +
                                                                is-amesenchymal cell differentiation involved in salivary gland development
                                                                part-ofmesenchymal cell fate commitment
                                                                is-aneural crest cell differentiation +
                                                        is-amesenchymal stem cell differentiation +
                                                        negatively-regulatesnegative regulation of stem cell differentiation +
                                                        is-aneuroblast differentiation +
                                                        positively-regulatespositive regulation of stem cell differentiation +
                                                        regulatesregulation of stem cell differentiation +
                                                        is-arespiratory basal cell differentiation
                                                        part-ofstem cell development +
                                                        part-ofstem cell fate commitment +


Gene_Ontology
        is-abiological_process
                is-adevelopmental process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                part-oforgan development
                                                        part-ofmesenchyme development
                                                                is-aendocardial cushion development +
                                                                is-agonadal mesoderm development
                                                                is-akidney mesenchyme development +
                                                                is-alateral mesoderm development +
                                                                is-alung-associated mesenchyme development +
                                                                part-ofmesenchymal cell differentiation [GO:0048762] (149 genes, 218 annotations)
                                                                        is-aamniotic stem cell differentiation +
                                                                        is-aangioblast cell differentiation
                                                                        part-ofmesenchymal cell development +
                                                                        is-amesenchymal cell differentiation involved in bone development
                                                                        is-amesenchymal cell differentiation involved in lung development
                                                                        is-amesenchymal cell differentiation involved in mammary gland development
                                                                        is-amesenchymal cell differentiation involved in renal system development +
                                                                        is-amesenchymal cell differentiation involved in salivary gland development
                                                                        part-ofmesenchymal cell fate commitment
                                                                        is-aneural crest cell differentiation +
                                                                part-ofmesenchyme morphogenesis +
                                                                is-ametanephric cortex development
                                                                is-aparaxial mesoderm development +
                                                                is-aproepicardium development
                                                                is-asclerotome development +
                                                                is-aseptum transversum development +


Gene_Ontology
        is-abiological_process
                is-amulticellular organismal process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                part-oforgan development
                                                        part-ofmesenchyme development
                                                                is-aendocardial cushion development +
                                                                is-agonadal mesoderm development
                                                                is-akidney mesenchyme development +
                                                                is-alateral mesoderm development +
                                                                is-alung-associated mesenchyme development +
                                                                part-ofmesenchymal cell differentiation [GO:0048762] (149 genes, 218 annotations)
                                                                        is-aamniotic stem cell differentiation +
                                                                        is-aangioblast cell differentiation
                                                                        part-ofmesenchymal cell development +
                                                                        is-amesenchymal cell differentiation involved in bone development
                                                                        is-amesenchymal cell differentiation involved in lung development
                                                                        is-amesenchymal cell differentiation involved in mammary gland development
                                                                        is-amesenchymal cell differentiation involved in renal system development +
                                                                        is-amesenchymal cell differentiation involved in salivary gland development
                                                                        part-ofmesenchymal cell fate commitment
                                                                        is-aneural crest cell differentiation +
                                                                part-ofmesenchyme morphogenesis +
                                                                is-ametanephric cortex development
                                                                is-aparaxial mesoderm development +
                                                                is-aproepicardium development
                                                                is-asclerotome development +
                                                                is-aseptum transversum development +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-multicellular organism process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                part-oforgan development
                                                        part-ofmesenchyme development
                                                                is-aendocardial cushion development +
                                                                is-agonadal mesoderm development
                                                                is-akidney mesenchyme development +
                                                                is-alateral mesoderm development +
                                                                is-alung-associated mesenchyme development +
                                                                part-ofmesenchymal cell differentiation [GO:0048762] (149 genes, 218 annotations)
                                                                        is-aamniotic stem cell differentiation +
                                                                        is-aangioblast cell differentiation
                                                                        part-ofmesenchymal cell development +
                                                                        is-amesenchymal cell differentiation involved in bone development
                                                                        is-amesenchymal cell differentiation involved in lung development
                                                                        is-amesenchymal cell differentiation involved in mammary gland development
                                                                        is-amesenchymal cell differentiation involved in renal system development +
                                                                        is-amesenchymal cell differentiation involved in salivary gland development
                                                                        part-ofmesenchymal cell fate commitment
                                                                        is-aneural crest cell differentiation +
                                                                part-ofmesenchyme morphogenesis +
                                                                is-ametanephric cortex development
                                                                is-aparaxial mesoderm development +
                                                                is-aproepicardium development
                                                                is-asclerotome development +
                                                                is-aseptum transversum development +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism cellular process
                                is-acellular developmental process
                                        is-acell differentiation
                                                is-astem cell differentiation
                                                        is-acardioblast differentiation +
                                                        is-ahematopoietic stem cell differentiation +
                                                        is-ahepatoblast differentiation
                                                        is-alimb basal epidermal cell differentiation +
                                                        is-amesenchymal cell differentiation [GO:0048762] (149 genes, 218 annotations)
                                                                is-aamniotic stem cell differentiation +
                                                                is-aangioblast cell differentiation
                                                                part-ofmesenchymal cell development +
                                                                is-amesenchymal cell differentiation involved in bone development
                                                                is-amesenchymal cell differentiation involved in lung development
                                                                is-amesenchymal cell differentiation involved in mammary gland development
                                                                is-amesenchymal cell differentiation involved in renal system development +
                                                                is-amesenchymal cell differentiation involved in salivary gland development
                                                                part-ofmesenchymal cell fate commitment
                                                                is-aneural crest cell differentiation +
                                                        is-amesenchymal stem cell differentiation +
                                                        negatively-regulatesnegative regulation of stem cell differentiation +
                                                        is-aneuroblast differentiation +
                                                        positively-regulatespositive regulation of stem cell differentiation +
                                                        regulatesregulation of stem cell differentiation +
                                                        is-arespiratory basal cell differentiation
                                                        part-ofstem cell development +
                                                        part-ofstem cell fate commitment +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism developmental process
                                is-acellular developmental process
                                        is-acell differentiation
                                                is-astem cell differentiation
                                                        is-acardioblast differentiation +
                                                        is-ahematopoietic stem cell differentiation +
                                                        is-ahepatoblast differentiation
                                                        is-alimb basal epidermal cell differentiation +
                                                        is-amesenchymal cell differentiation [GO:0048762] (149 genes, 218 annotations)
                                                                is-aamniotic stem cell differentiation +
                                                                is-aangioblast cell differentiation
                                                                part-ofmesenchymal cell development +
                                                                is-amesenchymal cell differentiation involved in bone development
                                                                is-amesenchymal cell differentiation involved in lung development
                                                                is-amesenchymal cell differentiation involved in mammary gland development
                                                                is-amesenchymal cell differentiation involved in renal system development +
                                                                is-amesenchymal cell differentiation involved in salivary gland development
                                                                part-ofmesenchymal cell fate commitment
                                                                is-aneural crest cell differentiation +
                                                        is-amesenchymal stem cell differentiation +
                                                        negatively-regulatesnegative regulation of stem cell differentiation +
                                                        is-aneuroblast differentiation +
                                                        positively-regulatespositive regulation of stem cell differentiation +
                                                        regulatesregulation of stem cell differentiation +
                                                        is-arespiratory basal cell differentiation
                                                        part-ofstem cell development +
                                                        part-ofstem cell fate commitment +


Gene_Ontology
        is-abiological_process
                is-asingle-organism process
                        is-asingle-organism developmental process
                                is-amulticellular organismal development
                                        part-ofsystem development
                                                part-oforgan development
                                                        part-ofmesenchyme development
                                                                is-aendocardial cushion development +
                                                                is-agonadal mesoderm development
                                                                is-akidney mesenchyme development +
                                                                is-alateral mesoderm development +
                                                                is-alung-associated mesenchyme development +
                                                                part-ofmesenchymal cell differentiation [GO:0048762] (149 genes, 218 annotations)
                                                                        is-aamniotic stem cell differentiation +
                                                                        is-aangioblast cell differentiation
                                                                        part-ofmesenchymal cell development +
                                                                        is-amesenchymal cell differentiation involved in bone development
                                                                        is-amesenchymal cell differentiation involved in lung development
                                                                        is-amesenchymal cell differentiation involved in mammary gland development
                                                                        is-amesenchymal cell differentiation involved in renal system development +
                                                                        is-amesenchymal cell differentiation involved in salivary gland development
                                                                        part-ofmesenchymal cell fate commitment
                                                                        is-aneural crest cell differentiation +
                                                                part-ofmesenchyme morphogenesis +
                                                                is-ametanephric cortex development
                                                                is-aparaxial mesoderm development +
                                                                is-aproepicardium development
                                                                is-asclerotome development +
                                                                is-aseptum transversum development +


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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory