Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLA2G2A
  • Mouse genes Pla2g2a
  • Rat genes Pla2g2a
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pla2g2a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0047498	calcium-dependent phospholipase A2 activity	PLA2G2A	IDA		Human	PMID:10358193
Molecular Function	GO:0047498	calcium-dependent phospholipase A2 activity	PLA2G2A	IDA		Human	PMID:25082876
Molecular Function	GO:0047498	calcium-dependent phospholipase A2 activity	Pla2g2a	IDA		Rat	PMID:9487151|RGD:2303763
Molecular Function	GO:0004623	phospholipase A2 activity	PLA2G2A	IDA		Human	PMID:17069818
Molecular Function	GO:0005543	phospholipid binding	PLA2G2A	IDA		Human	PMID:9032461
Cellular Component	GO:0005783	endoplasmic reticulum	PLA2G2A	IDA		Human	GO_REF:0000054
Cellular Component	GO:0070062	extracellular exosome	PLA2G2A	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	PLA2G2A	IDA		Human	PMID:17069818
Cellular Component	GO:0005615	extracellular space	PLA2G2A	HDA		Human	PMID:23580065
Cellular Component	GO:0005739	mitochondrion	Pla2g2a	HDA		Mouse	PMID:14651853
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Pla2g2a	IDA		Rat	PMID:11034413|RGD:8693682
Cellular Component	GO:0030141	secretory granule	Pla2g2a	IDA		Rat	PMID:9487151|RGD:2303763
Biological Process	GO:0008283	cell population proliferation	Pla2g2a	IGI	MGI:MGI:88039	Mouse	PMID:10451698
Biological Process	GO:0050830	defense response to Gram-positive bacterium	PLA2G2A	IMP		Human	PMID:10358193
Biological Process	GO:0008285	negative regulation of cell population proliferation	Pla2g2a	IGI	MGI:MGI:88039	Mouse	PMID:10451698
Biological Process	GO:0050680	negative regulation of epithelial cell proliferation	Pla2g2a	IGI	MGI:MGI:88039	Mouse	PMID:9288104
Biological Process	GO:0046473	phosphatidic acid metabolic process	PLA2G2A	IDA		Human	PMID:9032461
Biological Process	GO:0046470	phosphatidylcholine metabolic process	PLA2G2A	IDA		Human	PMID:25082876
Biological Process	GO:0046337	phosphatidylethanolamine metabolic process	PLA2G2A	IDA		Human	PMID:25082876
Biological Process	GO:0006644	phospholipid metabolic process	PLA2G2A	IDA		Human	PMID:17069818
Biological Process	GO:0006644	phospholipid metabolic process	Pla2g2a	IDA		Rat	PMID:9487151|RGD:2303763
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	PLA2G2A	IDA		Human	PMID:22837859
Biological Process	GO:0042127	regulation of cell population proliferation	Pla2g2a	IGI	MGI:MGI:94912	Mouse	PMID:10919675
Biological Process	GO:0042127	regulation of cell population proliferation	Pla2g2a	IGI	MGI:MGI:88039	Mouse	PMID:10716720
Biological Process	GO:0042127	regulation of cell population proliferation	Pla2g2a	IGI	MGI:MGI:88039	Mouse	PMID:11274413
Biological Process	GO:0042127	regulation of cell population proliferation	Pla2g2a	IGI	MGI:MGI:88039	Mouse	PMID:10919675
Biological Process	GO:0001936	regulation of endothelial cell proliferation	Pla2g2a	IGI	MGI:MGI:88039	Mouse	PMID:9159163
Biological Process	GO:0050678	regulation of epithelial cell proliferation	Pla2g2a	IGI	MGI:MGI:88039	Mouse	PMID:8978063
Biological Process	GO:0050678	regulation of epithelial cell proliferation	Pla2g2a	IGI	MGI:MGI:88039	Mouse	PMID:8978062
Biological Process	GO:1902563	regulation of neutrophil activation	PLA2G2A	IDA		Human	PMID:25082876
Biological Process	GO:0035019	somatic stem cell population maintenance	Pla2g2a	IGI	MGI:MGI:88039	Mouse	PMID:1541640

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern