Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PLA2G1B
  • Mouse genes Pla2g1b
  • Rat genes Pla2g1b
  • Zfish genes pla2g1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pla2g1b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	PLA2G1B	IDA		Human	PMID:7060561
Molecular Function	GO:0047498	calcium-dependent phospholipase A2 activity	PLA2G1B	IDA		Human	PMID:1420353
Molecular Function	GO:0047498	calcium-dependent phospholipase A2 activity	PLA2G1B	IDA		Human	PMID:17603006
Molecular Function	GO:0047498	calcium-dependent phospholipase A2 activity	PLA2G1B	IDA		Human	PMID:7060561
Molecular Function	GO:0047498	calcium-dependent phospholipase A2 activity	Pla2g1b	IDA		Rat	PMID:9487151|RGD:2303763
Molecular Function	GO:0004623	phospholipase A2 activity	PLA2G1B	IDA		Human	PMID:1918029
Molecular Function	GO:0004623	phospholipase A2 activity	Pla2g1b	IDA		Mouse	PMID:10531313
Molecular Function	GO:0004623	phospholipase A2 activity	Pla2g1b	IDA		Rat	PMID:14998370|RGD:1302902
Molecular Function	GO:0004623	phospholipase A2 activity	Pla2g1b	IDA		Rat	PMID:1918029|RGD:8553780
Molecular Function	GO:0005102	signaling receptor binding	PLA2G1B	IDA		Human	PMID:1918029
Molecular Function	GO:0005102	signaling receptor binding	PLA2G1B	IPI	UniProtKB:Q13018-1	Human	PMID:7721806
Molecular Function	GO:0005102	signaling receptor binding	PLA2G1B	IPI	UniProtKB:Q13018-2	Human	PMID:7721806
Molecular Function	GO:0005102	signaling receptor binding	Pla2g1b	IDA		Mouse	PMID:10066760
Molecular Function	GO:0005102	signaling receptor binding	Pla2g1b	IDA		Rat	PMID:1918029|RGD:8553780
Cellular Component	GO:0009986	cell surface	PLA2G1B	IDA		Human	PMID:1918029
Cellular Component	GO:0009986	cell surface	Pla2g1b	IDA		Rat	PMID:1918029|RGD:8553780
Cellular Component	GO:0005576	extracellular region	Pla2g1b	IDA		Mouse	PMID:10531313
Cellular Component	GO:0005615	extracellular space	PLA2G1B	IDA		Human	PMID:12860195
Cellular Component	GO:0005615	extracellular space	PLA2G1B	IDA		Human	PMID:7060561
Cellular Component	GO:0030141	secretory granule	Pla2g1b	IDA		Rat	PMID:9487151|RGD:2303763
Biological Process	GO:0019731	antibacterial humoral response	PLA2G1B	IDA		Human	PMID:12860195
Biological Process	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	PLA2G1B	IDA		Human	PMID:12860195
Biological Process	GO:0050830	defense response to Gram-positive bacterium	PLA2G1B	IDA		Human	PMID:12860195
Biological Process	GO:0006633	fatty acid biosynthetic process	PLA2G1B	IDA		Human	PMID:1918029
Biological Process	GO:0006633	fatty acid biosynthetic process	Pla2g1b	IDA		Rat	PMID:1918029|RGD:8553780
Biological Process	GO:0002227	innate immune response in mucosa	PLA2G1B	IDA		Human	PMID:12860195
Biological Process	GO:0016042	lipid catabolic process	PLA2G1B	IDA		Human	PMID:7060561
Biological Process	GO:0046470	phosphatidylcholine metabolic process	PLA2G1B	IDA		Human	PMID:17603006
Biological Process	GO:0046470	phosphatidylcholine metabolic process	PLA2G1B	IDA		Human	PMID:7060561
Biological Process	GO:0046471	phosphatidylglycerol metabolic process	PLA2G1B	IDA		Human	PMID:1420353
Biological Process	GO:0006644	phospholipid metabolic process	Pla2g1b	IDA		Rat	PMID:9487151|RGD:2303763
Biological Process	GO:0008284	positive regulation of cell population proliferation	PLA2G1B	IDA		Human	PMID:1918029
Biological Process	GO:0008284	positive regulation of cell population proliferation	Pla2g1b	IDA		Rat	PMID:1918029|RGD:8553780
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	PLA2G1B	IDA		Human	PMID:1918029
Biological Process	GO:1904635	positive regulation of podocyte apoptotic process	PLA2G1B	IDA		Human	PMID:25335547

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern