Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PKP3
  • Mouse genes Pkp3
  • Rat genes Pkp3
  • Zfish genes pkp3a,pkp3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pkp3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045294	alpha-catenin binding	PKP3	IPI	UniProtKB:Q9UI47	Human	PMID:23136403
Molecular Function	GO:0098641	cadherin binding involved in cell-cell adhesion	PKP3	HDA		Human	PMID:25468996
Molecular Function	GO:0050839	cell adhesion molecule binding	PKP3	IPI	UniProtKB:P14923	Human	PMID:20859650
Molecular Function	GO:0019899	enzyme binding	PKP3	IPI	UniProtKB:Q13283	Human	PMID:25225333
Molecular Function	GO:0019899	enzyme binding	PKP3	IPI	UniProtKB:Q92900	Human	PMID:25225333
Molecular Function	GO:0005515	protein binding	PKP3	IPI	UniProtKB:P11940	Human	PMID:25225333
Molecular Function	GO:0005515	protein binding	PKP3	IPI	UniProtKB:Q06787	Human	PMID:25225333
Molecular Function	GO:0005515	protein binding	PKP3	IPI	UniProtKB:Q8NA54	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PKP3	IPI	UniProtKB:P14136	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Pkp3	IPI	PR:Q02248	Mouse	PMID:17535849
Cellular Component	GO:0005912	adherens junction	PKP3	HDA		Human	PMID:25468996
Cellular Component	GO:0030054	cell junction	PKP3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0001533	cornified envelope	Pkp3	IDA		Mouse	PMID:26644517
Cellular Component	GO:0030057	desmosome	Pkp3	IDA		Mouse	PMID:14673151
Cellular Component	GO:1990124	messenger ribonucleoprotein complex	PKP3	IDA		Human	PMID:25225333
Cellular Component	GO:0005654	nucleoplasm	PKP3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	PKP3	IDA		Human	PMID:20859650
Biological Process	GO:0002159	desmosome assembly	PKP3	IMP		Human	PMID:20859650
Biological Process	GO:1902373	negative regulation of mRNA catabolic process	PKP3	IMP		Human	PMID:25225333
Biological Process	GO:0010628	positive regulation of gene expression	PKP3	IMP		Human	PMID:25225333
Biological Process	GO:0072659	protein localization to plasma membrane	PKP3	IMP		Human	PMID:20859650

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern