Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PIK3C2A
  • Mouse genes Pik3c2a
  • Rat genes Pik3c2a
  • Zfish genes pik3c2a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pik3c2a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016303	1-phosphatidylinositol-3-kinase activity	PIK3C2A	IDA		Human	PMID:10766823
Molecular Function	GO:0016303	1-phosphatidylinositol-3-kinase activity	PIK3C2A	IDA		Human	PMID:10805725
Molecular Function	GO:0016303	1-phosphatidylinositol-3-kinase activity	PIK3C2A	IDA		Human	PMID:11239472
Molecular Function	GO:0016303	1-phosphatidylinositol-3-kinase activity	PIK3C2A	IDA		Human	PMID:9337861
Molecular Function	GO:0016303	1-phosphatidylinositol-3-kinase activity	Pik3c2a	IDA		Mouse	MGI:MGI:6467676|PMID:10329640
Molecular Function	GO:0016303	1-phosphatidylinositol-3-kinase activity	Pik3c2a	IDA		Mouse	PMID:8663140
Molecular Function	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity	PIK3C2A	IDA		Human	PMID:10805725
Molecular Function	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity	PIK3C2A	IDA		Human	PMID:11239472
Molecular Function	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity	PIK3C2A	IDA		Human	PMID:9337861
Molecular Function	GO:0030276	clathrin binding	PIK3C2A	IDA		Human	PMID:11239472
Molecular Function	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity	PIK3C2A	IDA		Human	PMID:11239472
Molecular Function	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity	PIK3C2A	IDA		Human	PMID:9337861
Cellular Component	GO:0030136	clathrin-coated vesicle	PIK3C2A	IDA		Human	PMID:10766823
Cellular Component	GO:0030136	clathrin-coated vesicle	PIK3C2A	IDA		Human	PMID:11239472
Cellular Component	GO:0005737	cytoplasm	PIK3C2A	IDA		Human	PMID:21081650
Cellular Component	GO:0005829	cytosol	PIK3C2A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	PIK3C2A	HDA		Human	PMID:19056867
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	PIK3C2A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	PIK3C2A	HDA		Human	PMID:19946888
Cellular Component	GO:0005654	nucleoplasm	PIK3C2A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	PIK3C2A	IDA		Human	PMID:10766823
Cellular Component	GO:0005886	plasma membrane	PIK3C2A	IDA		Human	PMID:11239472
Cellular Component	GO:0005886	plasma membrane	PIK3C2A	IDA		Human	PMID:21081650
Cellular Component	GO:0005802	trans-Golgi network	PIK3C2A	IDA		Human	PMID:10766823
Cellular Component	GO:0005802	trans-Golgi network	PIK3C2A	IDA		Human	PMID:11239472
Cellular Component	GO:0031982	vesicle	PIK3C2A	IDA		Human	PMID:21081650
Biological Process	GO:0001525	angiogenesis	pik3c2a	IMP	ZFIN:ZDB-MRPHLNO-141209-5	Zfish	PMID:25171174
Biological Process	GO:1905037	autophagosome organization	Pik3c2a	IGI	MGI:MGI:2685045	Mouse	PMID:24098492
Biological Process	GO:0009267	cellular response to starvation	Pik3c2a	IGI	MGI:MGI:2685045	Mouse	PMID:24098492
Biological Process	GO:0006897	endocytosis	PIK3C2A	IMP		Human	PMID:21081650
Biological Process	GO:0046834	lipid phosphorylation	Pik3c2a	IDA		Mouse	MGI:MGI:80875|PMID:8663140
Biological Process	GO:0016236	macroautophagy	Pik3c2a	IGI	MGI:MGI:2685054	Mouse	PMID:24098492
Biological Process	GO:0071583	negative regulation of zinc ion transmembrane transport	Pik3c2a	IMP		Mouse	PMID:23823722
Biological Process	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process	Pik3c2a	IDA		Mouse	MGI:MGI:80875|PMID:8663140
Biological Process	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process	Pik3c2a	IGI	MGI:MGI:2685045	Mouse	PMID:24098492
Biological Process	GO:0010508	positive regulation of autophagy	PIK3C2A	IMP		Human	PMID:28910396
Biological Process	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	PIK3C2A	IMP		Human	PMID:26175229

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern