Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PIK3AP1
  • Mouse genes Pik3ap1
  • Rat genes Pik3ap1
  • Zfish genes pik3ap1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Pik3ap1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	Pik3ap1	IPI	UniProtKB:Q9EQ32	Mouse	MGI:MGI:3688344|PMID:15102471
Molecular Function	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	Pik3ap1	IDA		Mouse	MGI:MGI:5487531|PMID:20728433
Molecular Function	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	Pik3ap1	IDA		Mouse	MGI:MGI:5305504|PMID:22187458
Molecular Function	GO:0005515	protein binding	PIK3AP1	IPI	UniProtKB:P62993	Human	PMID:21706016
Molecular Function	GO:0005515	protein binding	PIK3AP1	IPI	UniProtKB:P62993	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	PIK3AP1	IPI	UniProtKB:P62993	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	PIK3AP1	IPI	UniProtKB:P62993	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	Pik3ap1	IPI	UniProtKB:P22366|UniProtKB:Q99JY1	Mouse	MGI:MGI:5305503|PMID:22187460
Molecular Function	GO:0005515	protein binding	Pik3ap1	IPI	PR:P26450	Mouse	PMID:11163197
Cellular Component	GO:0005737	cytoplasm	Pik3ap1	IDA		Mouse	PMID:11163197
Cellular Component	GO:0005829	cytosol	Pik3ap1	IDA		Mouse	MGI:MGI:5305504|PMID:22187458
Cellular Component	GO:0016020	membrane	Pik3ap1	IDA		Mouse	MGI:MGI:5305504|PMID:22187458
Cellular Component	GO:0005886	plasma membrane	Pik3ap1	IDA		Mouse	PMID:11163197
Biological Process	GO:0034122	negative regulation of toll-like receptor signaling pathway	Pik3ap1	IMP		Mouse	MGI:MGI:5487531|PMID:20728433
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	Pik3ap1	IMP		Mouse	MGI:MGI:5305503|PMID:22187460
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	Pik3ap1	IMP		Mouse	MGI:MGI:5305504|PMID:22187458
Biological Process	GO:0034123	positive regulation of toll-like receptor signaling pathway	Pik3ap1	IMP		Mouse	MGI:MGI:5487531|PMID:20728433
Biological Process	GO:0050727	regulation of inflammatory response	Pik3ap1	IMP		Mouse	MGI:MGI:5305503|PMID:22187460
Biological Process	GO:0034134	toll-like receptor 2 signaling pathway	Pik3ap1	IMP		Mouse	MGI:MGI:5305503|PMID:22187460
Biological Process	GO:0034142	toll-like receptor 4 signaling pathway	Pik3ap1	IMP		Mouse	MGI:MGI:5305503|PMID:22187460
Biological Process	GO:0034142	toll-like receptor 4 signaling pathway	Pik3ap1	IMP		Mouse	MGI:MGI:5305504|PMID:22187458
Biological Process	GO:0034154	toll-like receptor 7 signaling pathway	Pik3ap1	IMP		Mouse	MGI:MGI:5305504|PMID:22187458
Biological Process	GO:0034162	toll-like receptor 9 signaling pathway	Pik3ap1	IMP		Mouse	MGI:MGI:5305504|PMID:22187458
Biological Process	GO:0034162	toll-like receptor 9 signaling pathway	Pik3ap1	IMP		Mouse	MGI:MGI:5305503|PMID:22187460

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern