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Pik3ap1
Gene Detail
Symbol

Name
ID
Pik3ap1
phosphoinositide-3-kinase adaptor protein 1
MGI:1933177
Synonyms
1810044J04Rik, BCAP
Feature Type
protein coding gene
Genetic Map
Chromosome 19
34.61 cM, cytoband D1
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr19:41274218-41385070 bp, - strand
From NCBI annotation of GRCm38

  110853 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:12848  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Pik3ap1

Human
homologs
Human Homolog PIK3AP1, phosphoinositide-3-kinase adaptor protein 1
NCBI Gene ID 118788
neXtProt AC  NX_Q6ZUJ8
Human Synonyms  BCAP
Human Chr (Location)  10q24.1; chr10:96593312-96720522 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Chemically induced (ENU)(1) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for disruptions in this gene have abnormalities in B cell maturation.
 
Interactions
Pik3ap1 interacts with 22 markers (Mir216a, Mir300, Mir330, ...)
Expression
cDNA source data(37)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(39) cDNA(39)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000025017 (Evidence)
Entrez Gene83490 (Evidence)
UniGene222266
DFCITC1577535
DoTSDT.101277736, DT.101307238, DT.97357915
NIA Mouse Gene IndexU039035
Consensus CDS ProjectCCDS37987.1
International Mouse Knockout Project StatusPik3ap1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 83490 NCBI Gene Model | MGI Sequence Detail 110853 C57BL/6J ±  kb
transcript NM_031376 RefSeq | MGI Sequence Detail 2615 Not Specified 
polypeptide Q9EQ32 UniProt | EBI | MGI Sequence Detail 811 Not Applicable 

For the selected sequences
All sequences(30) RefSeq(4) UniProt(1)
Polymorphisms
SNPs within 2kb(980 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017893 DBB domain
Protein Ontology PR:000012714 phosphoinositide 3-kinase adapter protein 1
Graphical View of Protein Domain Structure
References
(Earliest) J:66479 Okada T, et al., BCAP: the tyrosine kinase substrate that connects B cell receptor to phosphoinositide 3-kinase activation. Immunity. 2000 Dec;13(6):817-27
(Latest) J:185495 Arnold CN, et al., A forward genetic screen reveals roles for Nfkbid, Zeb1, and Ruvbl2 in humoral immunity. Proc Natl Acad Sci U S A. 2012 Jul 3;
All references(35)
Other
accession IDs
MGI:1919285

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/21/2014
MGI 5.20
The Jackson Laboratory