Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PHIP
  • Mouse genes Phip
  • Rat genes Phip
  • Zfish genes phip
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Phip

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070577	lysine-acetylated histone binding	PHIP	IDA		Human	PMID:22464331
Molecular Function	GO:0005515	protein binding	PHIP	IPI	UniProtKB:P35568	Human	PMID:11018022
Molecular Function	GO:0005515	protein binding	PHIP	IPI	UniProtKB:P40337-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Phip	IPI	UniProtKB:P35570	Mouse	MGI:MGI:1928448|PMID:11018022
Cellular Component	GO:0005634	nucleus	PHIP	IDA		Human	PMID:25593309
Cellular Component	GO:0005634	nucleus	Phip	IDA		Mouse	PMID:17636024
Biological Process	GO:0008283	cell population proliferation	Phip	IGI	MGI:MGI:109334	Mouse	PMID:17636024
Biological Process	GO:0008283	cell population proliferation	Phip	IGI	MGI:MGI:96432	Mouse	PMID:17636024
Biological Process	GO:0007010	cytoskeleton organization	PHIP	IMP		Human	PMID:21834987
Biological Process	GO:0048144	fibroblast proliferation	Phip	IMP	MGI:MGI:4129907	Mouse	PMID:20816727
Biological Process	GO:0008286	insulin receptor signaling pathway	Phip	IDA		Mouse	PMID:11018022
Biological Process	GO:0043066	negative regulation of apoptotic process	Phip	IDA		Mouse	MGI:MGI:3723572|PMID:17636024
Biological Process	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	PHIP	IDA		Human	PMID:17636024
Biological Process	GO:0018105	peptidyl-serine phosphorylation	Phip	IDA		Mouse	PMID:17636024
Biological Process	GO:0008284	positive regulation of cell population proliferation	Phip	IMP		Mouse	MGI:MGI:3723572|PMID:17636024
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Phip	IDA		Mouse	MGI:MGI:3723572|PMID:17636024
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	Phip	IMP	MGI:MGI:4129907	Mouse	PMID:20816727
Biological Process	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway	Phip	IDA		Mouse	MGI:MGI:3723572|PMID:17636024
Biological Process	GO:0045840	positive regulation of mitotic nuclear division	Phip	IMP		Mouse	MGI:MGI:3723572|PMID:17636024
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	Phip	IDA		Mouse	PMID:17636024
Biological Process	GO:0010800	positive regulation of peptidyl-threonine phosphorylation	Phip	IDA		Mouse	PMID:17636024
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	PHIP	IDA		Human	PMID:17636024
Biological Process	GO:1904692	positive regulation of type B pancreatic cell proliferation	Phip	IGI	MGI:MGI:109334	Mouse	PMID:17636024
Biological Process	GO:1904692	positive regulation of type B pancreatic cell proliferation	Phip	IGI	MGI:MGI:96432	Mouse	PMID:17636024
Biological Process	GO:0006606	protein import into nucleus	Phip	IMP	MGI:MGI:4129907	Mouse	PMID:20816727
Biological Process	GO:0022604	regulation of cell morphogenesis	PHIP	IMP		Human	PMID:21834987
Biological Process	GO:0040008	regulation of growth	Phip	IMP	MGI:MGI:4129907	Mouse	PMID:20816727
Biological Process	GO:0001932	regulation of protein phosphorylation	Phip	IDA		Mouse	MGI:MGI:3723572|PMID:17636024
Biological Process	GO:0044342	type B pancreatic cell proliferation	Phip	IGI	MGI:MGI:96432	Mouse	PMID:17636024
Biological Process	GO:0044342	type B pancreatic cell proliferation	Phip	IGI	MGI:MGI:109334	Mouse	PMID:17636024

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern