Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes PHACTR1
  • Mouse genes Phactr1
  • Rat genes Phactr1
  • Zfish genes phactr1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Phactr1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	Phactr1	IDA		Mouse	MGI:MGI:5487491|PMID:22976292
Molecular Function	GO:0005515	protein binding	PHACTR1	IPI	UniProtKB:Q9HC52	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	PHACTR1	IPI	UniProtKB:Q9NWQ9	Human	PMID:32296183
Molecular Function	GO:0008157	protein phosphatase 1 binding	Phactr1	IDA		Rat	PMID:15107502|RGD:1303990
Cellular Component	GO:0005829	cytosol	Phactr1	IDA		Mouse	MGI:MGI:5487491|PMID:22976292
Cellular Component	GO:0005634	nucleus	Phactr1	IDA		Mouse	MGI:MGI:5487491|PMID:22976292
Cellular Component	GO:0045202	synapse	Phactr1	IDA		Rat	PMID:15107502|RGD:1303990
Biological Process	GO:0031532	actin cytoskeleton reorganization	Phactr1	IMP		Mouse	MGI:MGI:5487491|PMID:22976292
Biological Process	GO:0031032	actomyosin structure organization	PHACTR1	IMP		Human	PMID:22976292
Biological Process	GO:0031032	actomyosin structure organization	Phactr1	IMP		Mouse	MGI:MGI:5487491|PMID:22976292
Biological Process	GO:0048870	cell motility	PHACTR1	IMP		Human	PMID:22976292
Biological Process	GO:0021987	cerebral cortex development	Phactr1	IMP		Mouse	MGI:MGI:6316857|PMID:30256902
Biological Process	GO:0140059	dendrite arborization	Phactr1	IMP		Mouse	MGI:MGI:6316857|PMID:30256902
Biological Process	GO:2001222	regulation of neuron migration	Phactr1	IMP		Mouse	MGI:MGI:6316857|PMID:30256902
Biological Process	GO:0042325	regulation of phosphorylation	Phactr1	IDA		Rat	PMID:15107502|RGD:1303990
Biological Process	GO:0043149	stress fiber assembly	PHACTR1	IMP		Human	PMID:22976292
Biological Process	GO:0043149	stress fiber assembly	Phactr1	IMP		Mouse	MGI:MGI:5487491|PMID:22976292
Biological Process	GO:0001944	vasculature development	phactr1	IMP	ZFIN:ZDB-MRPHLNO-170405-1	Zfish	PMID:27792790

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern